Project description DEENESFRITPL A new treatment for stroke A stroke is caused when the blood supply to part of the brain is interrupted, leading to tissue damage. Currently, there are no effective treatments for stroke; only rehabilitation approaches to treat resulting neurological impairment. Funded by the European Innovation Council, the EDVance project will undertake a clinical trial on the disruptive new drug EDV2209. This drug is a result of years of research on cerebral blood circulation and stroke and functions by maintaining the blood vessels in the brain open to oxygen and nutrients. Preventing brain tissue damage after stroke is paramount for minimising its devastating consequences. Show the project objective Hide the project objective Objective Despite tremendous research efforts and a large number of clinical trials focused on developing treatments for stroke, the field's current state remains dismal. There are, at present, no efficient treatments nor promising drug candidates for this lethal and disabling condition. A different perspective with a new approach is therefore desperately needed. Edvince's drug discovery and development is born out of founder and Professor Lars Edvinsson's extensive, fundamental and pioneering research of cerebral circulation, receptor regulation, stroke and migraines. Edvince is now ready to conduct the first clinical trial in 2022 with its innovative and disruptive lead drug EDV2209, an orphan drug for the treatment of brain ischemia associated with severe subarachnoid hemorrhage (SAH). The drug helps to keep the blood vessels in the brain open, allowing brain cells to receive oxygen and nutrients to prevent brain damage. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverymedical and health sciencesbasic medicineneurologystroke Programme(s) HORIZON.3.1 - The European Innovation Council (EIC) Main Programme HORIZON.3.1.2 - The Accelerator Topic(s) HORIZON-EIC-2021-ACCELERATOROPEN-01 - EIC Accelerator Open 2021 Call for proposal HORIZON-EIC-2021-ACCELERATOROPEN-01 See other projects for this call Funding Scheme HORIZON-AG - HORIZON Action Grant Budget-Based Coordinator EDVINCE AKTIEBOLAG Net EU contribution € 2 500 000,00 Address Medicon village 223 81 Lund Sweden See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Södra Sverige Sydsverige Skåne län Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 1 922 831,25
