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Synthesis, self-aggregation and properties of nano-objects in chemistry, biology and material science

Final Activity Report Summary - NANOTOOL (Synthesis, self-aggregation and properties of nano-objects in chemistry, biology and material science)

Our EST site offered fellowships for trainings on nano-objects made of surfactant, metal nanoparticles or dendrimer / polymers. Those three fields are based on three different types of chemistry but lead to common applications (in biology, material science, catalysis,...) and encountered similar drawbacks or difficulties (stability and dispersibility in solution, processability, organisation on surface...). Laboratory intersectorial projects were therefore proposed in order to work at the frontiers between two research fields. The objective was to apply knowledge of one type of nano-objects to one other, leading presumably to highly innovative research projects. This is indeed the case: a large majority of the scientific productions of the EST site is related to such intersectorial projects, which correspond to circa 50 % of the fellow months. Multidisciplinary projects were designed to work on a specific type of nano-objects but from the synthesis to the applications of these systems. Such trainings led to new or reinforced interactions with European laboratories. New molecular systems for photodynamic therapy against cancer or to create new efficient in vitro HIV inhibitors, dispersable metal or metal oxide nanoparticles for sensor or electronic applications, material with liquid crystal and magnetic properties etc. are examples of research work performed during the 4 years of the EST site.

The research results of our EST site are currently around 50 papers, patents, participations to a congress etc. 60 % of this scientific production is related to the intersectorial project demonstrating the efficiency of the proposed strategy. All our fellows will (or have already) defend a PhD thesis: many of them have made this choice after their training in our EST site, which has therefore strongly promoted the scientific studies at the highest level.

In general, for each open position, many applications were received and all our proposed fellowships have been filled by students having an european citizenship. Those facts demonstrated the demand at the European level of such training.

This project has also created new bonds between the training site and European laboratories but also within the training site, it has induced many collaborations and cross-fertilisation of fields existing in our training site. Our laboratories have therefore gained in efficiency and visibility thanks to this EST program. The overall satisfaction of the researchers and the fellows of our site is very high.