Objective
The objective of the project is to provide postgraduate students, a pluri-disciplinary qualification for future career in medicinal chemistry, through research training, focused on two of the most important human health world problems: cancer and parasite diseases, and through additional training courses.
Medicinal chemistry has undergone deep changes during these last years with the emergence of new techniques and tools, in particular related to the progress of the genome knowledge. The goal of the network is the training in the techniques of lead discovery, rational drug design, organic synthesis, bioassays, cell biology, in one training site, with three academic partners involved in medicinal chemistry and an inter-related SME partner (Aureus Pharma) involved in bio-informatics.
The core of research training will be devoted to the search of new hits through natural product chemistry (extraction, structure determination and synthesis), and through mechanism-based drug design, including in silico approaches.
Numerous aspects of organic synthesis (asymmetric synthesis, organo-metallic chemistry, fluorine chemistry) are then essential to improve, from an initial 'hit', the biological activity, the physico-chemical properties for better pharmacological profile, to decrease toxicity, and to bring new tools for a better knowledge of mechanisms of action.
Additional training activities on other facets in the drug development or on fundamental knowledge are also available, through the Doctoral School, in other laboratories of the campus, through the collaboration with start-ups implemented on the site, and through national and international collaborations.
A complete training of young researchers in medicinal chemistry is essential for future, both in academia and industry, where discovery of new drugs rests mainly on the ability to use complementary approaches.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences health sciences infectious diseases malaria
- medical and health sciences basic medicine medicinal chemistry
- medical and health sciences basic medicine pharmacology and pharmacy drug resistance
- medical and health sciences clinical medicine oncology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-2
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
ORSAY
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.