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Prospective cohort studies of children with substantial medical diagnostic exposure

Objective

The growing use of diagnostic X-rays and of high-dose techniques (CT, interventions) in children and adolescents is a topic of concern in radiological protection. Studies of other populations indicate that children are generally more sensitive to health effects of radiation than adults. In addition, children have a longer life-span to express any radiation-related health effect and, because of their smaller mass children, may receive higher doses to specific organs from these procedures if examination protocols are not adapted. Procedures of particular concern include: the use of CT in children (which delivers doses that are substantially greater than those from conventional X-rays); interventional cardiology, in which fluoroscopy is used to guide small instruments such as catheters through blood vessels (which, if repeated, can deliver doses of several hundred mGy to specific organs); and the use of repeated X-rays for monitoring respiratory, cardiac and digestive pathologies in premature babies (for repeated procedures, cumulative doses range up to a few mGy – and premature babies could be particularly sensitive to radiation induced diseases). Because the health effects of these low doses of radiation are expected to be relatively small, trans-national collaborative studies are needed to ensure sufficient statistical power to study these effects. In this project we seek support to assemble a critical mass of scientists involved in the study of medical radiation exposures and health effects of radiation dispersed throughout Europe with the aim of: ● Assessing the feasibility of establishing prospective trans-national cohorts suitable for long term follow up (including evaluation of the statistical power of the study) ● If the feasibility is demonstrated: - Making recommendations for future research needs including populations suitable for long term follow-up; - Developing specific project proposals, including study protocols and procedures for follow-up.

Field of science

  • /medical and health sciences/basic medicine/pathology
  • /medical and health sciences/clinical medicine/cardiology

Call for proposal

FP7-Fission-2007
See other projects for this call

Funding Scheme

CSA-SA - Support actions

Coordinator

CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER
Address
150 Cours Albert Thomas
69372 Lyon Cedex 08
France
Activity type
Other
EU contribution
€ 114 735,24
Administrative Contact
Olaf Kelm (Dr.)

Participants (8)

SATEILYTURVAKESKUS
Finland
EU contribution
€ 10 000
Address
Laippatie 4
00880 Helsinki
Activity type
Research Organisations
Administrative Contact
Jaana Mannonen (Ms.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 10 000
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Caroline Hamilton (Ms.)
UNIVERSITY OF NEWCASTLE UPON TYNE
United Kingdom
EU contribution
€ 10 000
Address
Kings Gate
NE1 7RU Newcastle Upon Tyne
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Helen Gallon (Ms.)
FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL
Spain
EU contribution
€ 95 195,76
Address
Calle Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
Administrative Contact
Gemma Perelló (Ms.)
INSTITUT GUSTAVE ROUSSY
France
EU contribution
€ 10 000
Address
Rue Camille Desmoulins 39
94805 Villejuif
Activity type
Research Organisations
Administrative Contact
Arnauld Forest (Mr.)
KRAEFTENS BEKAEMPELSE
Denmark
EU contribution
€ 10 000
Address
Strandboulevarden 49
2100 Koebenhavn
Activity type
Research Organisations
Administrative Contact
Claus Skytte Rasmussen (Mr.)
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Netherlands
EU contribution
€ 10 000
Address
Plesmanlaan 121
1066 CX Amsterdam
Activity type
Research Organisations
Administrative Contact
H.G.A.M. Van Luenen (Dr.)
UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ
Germany
EU contribution
€ 10 000
Address
Langenbeckstrasse 1
55131 Mainz
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Silvia Tschauder (Dr.)