Objective This is a multi-disciplinary training programme focussed on the experimental and clinical problems associated with axonal damage and repair in the central nervous system. This is a central feature of a wide variety of disorders of the CNS. Future advances in this area depend on training a cohort of young researches with multiple skills. The programme encompasses ten academic and two commercial organisations. Each student will be trained in a variety of theoretical and technical approaches, based on the complementary expertise of the collaborating partners. In addition, there will be a strong emphasis on the commercial exploitation and development of potential new therapies. The individual projects are strongly cross-disciplinary, and a series of workshops, seminars and online tutorials will ensure the collective resources of each participant being available to each student. These will foster a sense of collegiality amongst the students themselves, and knowledge of the work going on in the labs of the consortium. The programme will have a common organisation strategy, with a balance between control by the coordinators and delegation to individual laboratories. The topics themselves range from studies on the molecular biology of gene expression during axonal damage and regeneration, through cellular approaches for rescuing axons, artificial systems for growing and studying axons in vitro, the use of stem cells as regenerative procedures, advanced imaging techniques for assessing axonal integrity, studies on ways to alter axonal plasticity, pharmacological approaches to preventing or restoring axonal damage, new surgical and experimental methods for studying axonal structure and function, tests of recovery (including both physiological and behavioural techniques) and the contribution of axonal malfunction to animal models of specific diseases. Students will also be taught the avenues available for commercial exploitation of experimental findings. Fields of science natural sciencesbiological sciencesneurobiologymedical and health sciencesmedical biotechnologycells technologiesstem cellsnatural sciencesbiological sciencesmolecular biology Keywords MS PD axon brain damage gene expression grafts growth factors myelin plasticity spinal cord stem cells stroke Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) PEOPLE-2007-1-1-ITN - Marie Curie Action: " Networks for Initial Training" Call for proposal FP7-PEOPLE-2007-1-1-ITN See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Address Trinity lane the old schools CB2 1TN Cambridge United Kingdom See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Administrative Contact Keith Cann (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Participants (12) Sort alphabetically Sort by EU Contribution Expand all Collapse all MAX IV Laboratory, Lund University Sweden EU contribution € 433 384,00 Address Paradisgatan 5c 22100 Lund See on map Region Södra Sverige Sydsverige Skåne län Activity type Higher or Secondary Education Establishments Administrative Contact Birgitta Larsson (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 420 164,00 Address Rue michel ange 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Béatrice Saint-Cricq (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK Poland EU contribution € 323 803,00 Address Ul. ludwika pasteura 3 02 093 Warszawa See on map Region Makroregion województwo mazowieckie Warszawski stołeczny Miasto Warszawa Activity type Research Organisations Administrative Contact Marta Rucinska (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITAT AUTONOMA DE BARCELONA Spain EU contribution € 394 017,00 Address Edif a campus de la uab bellaterra cerdanyola v 08193 Cerdanyola del valles See on map Region Este Cataluña Barcelona Activity type Higher or Secondary Education Establishments Administrative Contact Genoveva Martinez (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITA DEGLI STUDI DI TORINO Italy EU contribution € 418 696,00 Address Via giuseppe verdi 8 10124 Torino See on map Region Nord-Ovest Piemonte Torino Activity type Higher or Secondary Education Establishments Administrative Contact Donatella Amadori (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data University of Zurich Switzerland EU contribution € 455 125,00 Address Ramistrasse 71 8006 Zurich See on map Activity type Higher or Secondary Education Establishments Administrative Contact Anita Buchli (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data FONDAZIONE SANTA LUCIA Participation ended Italy EU contribution € 0,00 Address Via ardeatina 306 00179 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Antonio Ierna (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE Czechia EU contribution € 340 258,00 Address Videnska 1083 14220 Praha 4 See on map Region Česko Praha Hlavní město Praha Activity type Research Organisations Administrative Contact James Dutt (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW Netherlands EU contribution € 410 762,00 Address Kloveniersburgwal 29 het trippenhuis 1011 JV Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Research Organisations Administrative Contact Cor Van Leeuwen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data MILTENYI BIOTEC GMBH Germany EU contribution € 185 782,00 Address Friedrich ebert strasse 68 51429 Bergish gladbach See on map Region Nordrhein-Westfalen Köln Rheinisch-Bergischer Kreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Michael Apel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data PHARMAXON SAS Participation ended France EU contribution € 189 989,00 Address Parc scientifique de luminy 13288 Marseille See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Pascal Deschaseaux (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data Istituto Nazionale di Neuroscienze Italy EU contribution € 418 696,00 Address C.so raffaello 30 10125 Torino See on map Activity type Other Administrative Contact Claudio Saladini (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data