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Axonal regeneration, plasticity & stem cells

Objective

This is a multi-disciplinary training programme focussed on the experimental and clinical problems associated with axonal damage and repair in the central nervous system. This is a central feature of a wide variety of disorders of the CNS. Future advances in this area depend on training a cohort of young researches with multiple skills. The programme encompasses ten academic and two commercial organisations. Each student will be trained in a variety of theoretical and technical approaches, based on the complementary expertise of the collaborating partners. In addition, there will be a strong emphasis on the commercial exploitation and development of potential new therapies. The individual projects are strongly cross-disciplinary, and a series of workshops, seminars and online tutorials will ensure the collective resources of each participant being available to each student. These will foster a sense of collegiality amongst the students themselves, and knowledge of the work going on in the labs of the consortium. The programme will have a common organisation strategy, with a balance between control by the coordinators and delegation to individual laboratories. The topics themselves range from studies on the molecular biology of gene expression during axonal damage and regeneration, through cellular approaches for rescuing axons, artificial systems for growing and studying axons in vitro, the use of stem cells as regenerative procedures, advanced imaging techniques for assessing axonal integrity, studies on ways to alter axonal plasticity, pharmacological approaches to preventing or restoring axonal damage, new surgical and experimental methods for studying axonal structure and function, tests of recovery (including both physiological and behavioural techniques) and the contribution of axonal malfunction to animal models of specific diseases. Students will also be taught the avenues available for commercial exploitation of experimental findings.

Field of science

  • /medical and health sciences/medical biotechnology/cells technologies/stem cells
  • /natural sciences/biological sciences/molecular biology

Call for proposal

FP7-PEOPLE-2007-1-1-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 449 324
Administrative Contact
Keith Cann (Mr.)

Participants (12)

LUNDS UNIVERSITET
Sweden
EU contribution
€ 433 384
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Birgitta Larsson (Ms.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
EU contribution
€ 420 164
Address
Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
Administrative Contact
Béatrice Saint-Cricq (Ms.)
INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK
Poland
EU contribution
€ 323 803
Address
Ul. Ludwika Pasteura 3
02 093 Warszawa
Activity type
Research Organisations
Administrative Contact
Marta Rucinska (Ms.)
UNIVERSIDAD AUTONOMA DE BARCELONA
Spain
EU contribution
€ 394 017
Address
Calle Campus Universitario Sn Cerdanyola V
08290 Cerdanyola Del Valles
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Genoveva Martinez (Ms.)
UNIVERSITA DEGLI STUDI DI TORINO
Italy
EU contribution
€ 418 696
Address
Via Giuseppe Verdi 8
10124 Torino
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Donatella Amadori (Ms.)
UNIVERSITAT ZURICH
Switzerland
EU contribution
€ 455 125
Address
Ramistrasse 71
8006 Zürich
Activity type
Other
Administrative Contact
Anita Buchli (Dr.)
FONDAZIONE SANTA LUCIA

Participation ended

Italy
Address
Via Ardeatina 306
00179 Roma
Activity type
Research Organisations
Administrative Contact
Antonio Ierna (Dr.)
USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
Czechia
EU contribution
€ 340 258
Address
Videnska 1083
14220 Praha 4
Activity type
Research Organisations
Administrative Contact
James Dutt (Mr.)
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
Netherlands
EU contribution
€ 410 762
Address
Kloveniersburgwal 29 Het Trippenhuis
1011 JV Amsterdam
Activity type
Other
Administrative Contact
Cor Van Leeuwen (Mr.)
MILTENYI BIOTEC GMBH
Germany
EU contribution
€ 185 782
Address
Friedrich Ebert Strasse 68
51429 Bergish Gladbach
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michael Apel (Dr.)
PHARMAXON SAS

Participation ended

France
EU contribution
€ 189 989
Address
Parc Scientifique De Luminy
13288 Marseille
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Pascal Deschaseaux (Dr.)
Istituto Nazionale di Neuroscienze
Italy
EU contribution
€ 418 696
Address
C.so Raffaello 30
10125 Torino
Activity type
Other
Administrative Contact
Claudio Saladini (Dr.)