Objective
The evolution of eukaryotes required creation of protein targeting pathways to ensure discrete populations of proteins could be sent into each compartment. Various compartments, such as mitochondria, plastids, the nucleus and peroxisomes are eukaryote-spec ific and building protein targeting pathways for these compartments depended on the de novo creation of specific molecular machines. The purpose of this project is to search for and characterize components of equivalent molecular machines in the membranes of the mitochondria-related organelles found in some of the ancient protist species that represent significant parasites of humans. Candidates of TOM, TIM and PAM complex components involved in protein import into mitochondria-related organelles of Giardia intestinalis Entamoeba histolytica and Trichomonas vaginalis will be characterized. Our aim is to use comparative analyses to understand how a defined set of such molecular machines were created, and mechanistic details of how they provide their function in protein transport across membranes in each of the organisms in which they are found.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences evolutionary biology
- natural sciences biological sciences molecular biology molecular evolution
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-6
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
OIF - Marie Curie actions-Outgoing International Fellowships
Coordinator
PRAGUE 2
Czechia
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.