Objective
Within the PigSNP project SNPs will be identified that are known to be segregating within commercial European pig breeds. Using the Solexa sequencing technique a representation of the genome is directly sequenced to high redundancy. This is achieved by digesting the DNA with a restriction enzyme and sequencing fragments within a specific size range (i.e. 250 bp). The strategy used is based on sequencing a mixture of the DNA from 5 individuals of a single commercial breed to 20 X depth. Furthermore, the use of 5 individuals per breed (10 haplotypes) will ensure the identification of SNPs with high minor allele frequencies. This approach ensures that SNPs identified will be informative within the commercial line and therefore will be useful not only in experimental QTL crosses but also for genomic selection in current commercial breeding lines. The combination of new generation sequence technology (Solexa) combined with WITHIN breed SNP identification of major SNPs is particular innovative and timely. The SNPs identified will be available to be included in high density SNP panels (within existing international ongoing collaborations) that will be used to genotype available commercial pig breeds. This will aid in the further fine mapping of previously identified QTL within these commercial crosses. Within the project we will use the identified SNPs for fine mapping 2-3 previously identified QTL on chromosomes 2 and 4 identified within an experimental MeishanxEuropean white cross and within a commercial finisher population respectively. Both populations have been used extensively for the identification of several QTL for fatness, carcass and meat quality traits. Within the project it is aimed to identify between 10 and 20 thousand SNPs each for 4 different commercial breeds. QTL fine mapping will be done using the Illumina Golden Gate assay.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agricultural biotechnology marker assisted selection
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences genetics chromosomes
- natural sciences biological sciences genetics genomes
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-2-1-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
6708 PB Wageningen
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.