Expanding the Potential of in vitro Compartmentalised Screening and Selection Approaches

Project Information

EXIVC

Grant agreement ID: 220701

Project closed

Start date 1 March 2008

End date 28 February 2010

Funded under

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Total cost € 178 874,06

EU contribution € 178 874,06

Coordinated by

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Objective

In vitro selections offer the potential to select from large libraries, with fewer constraints than current cell-based selections. The key practical consideration in directed evolution of functional biomolecules is the linkage of genotype and phenotype, which can be provided by water-in-oil emulsion droplets that act as femtolitre reactors. Novel applications for catalytic selections of cellulases, key enzyme in teh production of bio-fuels, will be developed by in vitro compartmentalisation techniques in microfluidic devices that the host group has recently developed.

Fields of science

• engineering and technology › industrial biotechnology › biomaterials › biofuels
• natural sciences › biological sciences › biochemistry › biomolecules › proteins › enzymes

Keywords

• Biomedical engineering
• Molecular evolution

Programme(s)

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Topic(s)

• PEOPLE-2007-4-2.IIF - Marie Curie Action: "International Incoming Fellowships"

Call for proposal

FP7-PEOPLE-2007-4-2-IIF
See other projects for this call

Funding Scheme

MC-IIF - International Incoming Fellowships (IIF)

Coordinator

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

• EU contribution: € 178 874,06
• Address: TRINITY LANE THE OLD SCHOOLS ; CB2 1TN Cambridge ; United Kingdom
• Region: East of England › East Anglia › Cambridgeshire CC
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Dawn Barker (Ms.)
• Total cost: No data