Skip to main content

Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics

Objective

In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assay developers, aims to develop quality guidelines for molecular in vitro diagnostics and to standardize the pre-analytical workflow in related procedures. Regarding the second point, SPIDIA aims to develop modern pre-analytical tools for diagnostics improving the stabilisation, handling and study of free biomolecules within blood, plasma, serum, tissues and tumours. Recent discoveries have revealed that RNA, DNA or proteins, released from pathological sites, like tumour cells or Alzheimer’s disease (AD) brain lesions, into the blood or as a secondary blood based response to the disease can serve as biomarkers for early and reliable molecular diagnosis of such debilitating diseases. Further discoveries have shown that the cellular profiles of these molecules and structures in clinical samples can change during transport and storage thus making clinical assay results and pharmaceutical research unreliable or even impossible. It will therefore be a decisive prerequisite for future and current diagnostic assays to develop standards and new technologies, tools and devices that eliminate the human error in the pre-analytical steps of in vitro diagnostics. At this crucial moment in the development of molecular diagnostics, SPIDIA proposes an IP that reunites 7 private research companies (including 4 SMEs), 1 private research institute, 6 public research organisms, including universities, hospitals and biobanks, one management SME and an official European Standards Organisation. This strong consortium is balanced and empowered to maximise the impacts of in vitro diagnostics on human health.

Field of science

  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins
  • /natural sciences/biological sciences/biochemistry/biomolecules
  • /social sciences/social and economic geography/transport
  • /medical and health sciences/basic medicine/neurology/alzheimer

Call for proposal

FP7-HEALTH-2007-B
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

QIAGEN GMBH
Address
Qiagen Strasse 1
40724 Hilden
Germany
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 2 048 002
Administrative Contact
Ann Vinckier (Dr.)

Participants (16)

MEDIZINISCHE UNIVERSITAT GRAZ
Austria
EU contribution
€ 1 107 412
Address
Auenbruggerplatz 2
8036 Graz
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sandra Hagauer (Ms.)
CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE
Italy
EU contribution
€ 340 020
Address
Piazza San Marco 4
50121 Firenze
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Francesca Di Gloria (Dr.)
TATAA BIOCENTER AB
Sweden
EU contribution
€ 539 680
Address
Odinsgatan 28
411 03 Goteborg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Anne Hansen (Ms.)
PREANALYTIX GMBH
Switzerland
Address
Feldbachstrasse
8634 Hombrechtikon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ann Vinckier (Dr.)
DIAGENIC ASA
Norway
EU contribution
€ 579 374
Address
Grenseveien 92
0663 Oslo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ruben Ekbråten (Mr.)
AROS APPLIED BIOTECHNOLOGY AS
Denmark
EU contribution
€ 604 410
Address
Brendstrupgaardsvej 102
8200 Aarhus
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Brian Sorensen (Dr.)
DAKO DENMARK A/S
Denmark
EU contribution
€ 640 200
Address
Produktionsvej 42
2600 Glostrup
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Rosa Winther (Ms.)
ACIES SAS

Participation ended

France
EU contribution
€ 16 721
Address
69 Rue De La République
69002 Lyon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Patrick Duvarry (Mr.)
BIOTECHNOLOGICKY USTAV AV CR VVI
Czechia
EU contribution
€ 275 000
Address
Videnska 1083
142 20 Prague
Activity type
Research Organisations
Administrative Contact
Lukas Vesely (Mr.)
COMITE EUROPEEN DE NORMALISATION
Belgium
EU contribution
€ 100 000
Address
Rue De La Science 23
1040 Bruxelles
Activity type
Other
Administrative Contact
Alexandre Della Faille De Leverghem (Mr.)
IMMUNID TECHNOLOGIES
France
EU contribution
€ 419 952
Address
Allee Des Romantiques 43
38100 Grenoble
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Anne Bagard (Dr.)
UNIVERSITA DEGLI STUDI DI FIRENZE
Italy
EU contribution
€ 1 142 056
Address
Piazza San Marco 4
50121 Florence
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Stefano Milani (Prof.)
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 549 183
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Theo Van Der Poel (Mr.)
TECHNISCHE UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 286 534
Address
Arcisstrasse 21
80333 Muenchen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ulrike Ronchetti
FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI
Italy
EU contribution
€ 95 000
Address
Via Venezian 1
20133 Milan
Activity type
Research Organisations
Administrative Contact
Antonio Cannarozzo (Mr.)
NOVAMEN SAS
France
EU contribution
€ 238 252
Address
Rue De La République 69
69002 Lyon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Vincent Grosbois (Mr.)