Objective
Cruciferous plants, which include the economically important Brassica vegetables and the model plant Arabidopsis, produce indole glucosinolates and indole alkaloids. These bioactive natural products are known to confer specific pest resistance to crucifer plants. For humans, the compounds are known as flavour compounds, cancer-preventive compounds, and biopesticides. Indole-3-acetaldoxime (IAOx) is an intermediate in biosynthesis of indole glucosinolates and indole alkaloids, and is a precursor for the plant hormone indole-3-acetic acid (IAA), that is essential in many aspects of plant growth and development, although its biosynthesis remains elusive, despite substantial efforts.
Recently, it was shown that camalexin (the indole alkaloid of Arabidopsis) was synthesized directly from IAOx, and that several aUhigh-auxina mutants in Arabidopsis obtained their phenotype due to blockage of the glucosinolate pathway downstream from IAOx. The emerging knowledge of IAOx metabolism has unravelled a new exciting area on the borderline between primary and secondary metabolism.
This project will combine bioinformatics with state-of-the-art technologies for gene discovery in the biosynthesis of IAA and camalexin, areas where Europe traditionally has been at the forefront. The inter- and multidisciplinary project is expected to generate biotechnological tools for improving plant resistance and performance, nutritional quality of plant-derived products, as well as for producing high-value compounds in microorganisms.
The project involves attraction of a top-class young Chinese scientist to an internationally leading Community lab, followed by a reintegration phase where the acquired high level scientific and managerial competence will be implemented to advance research in natural products, to build a future independent career, and serve as a basis for future collaboration between the two host organisations for mutual benefit of Europe and China.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries agriculture horticulture vegetable growing
- natural sciences biological sciences microbiology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IIF - Marie Curie actions-Incoming International Fellowships
Coordinator
KOBENHAVN
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.