Objective
This project addresses a research topic relevant to the field of life sciences, genomics and biotechnology for health in FP6. Protein tyrosine phosphorylation is a key mechanism for signal transduction and the regulation of a broad set of physiological pro cesses that are characteristic to multi-cellular organisms. Recently the entire repertoire of the human protein tyrosine phosphatase (PTP) genes has been discovered. From the few studies on PTPs it is becoming apparent that PTPs tend to be very specific and to have non-redundant unique functions. Therefore, it is essential to understand the physiological functions of the individual PTPs. One of the newly discovered PTPs is the Histidine domain protein tyrosine phosphatase (HD-PTP), which has been suggested t o be a tumour suppressor. This project attempts to investigate through a multidisciplinary approach the physiological role of this PTP.
Several objectives are proposed:
i) to find the physiological relevant proteins that interact with HD-PTP and and their importance for cell physiology;
ii) to understand the role of HD-PTP structural domains for its function;
iii) to investigate the role of HD-PTP in vertebrate development.
The project is planned to be accomplished in 3 years being performed by a small team of researchers including the applicant. The project is expected to be an opportunity for the applicant to put into practice her scientific knowledge she gained in the USA, the country where she spent the last 10 years and to help the applicant receive a s table position as a researcher in her home country, thus, contributing to the reversing and cancelling the effects of the European brain drain to third countries. At the same time, the project will allow the applicant and the host institution to develop lasting co-operation with scientists from the USA.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences physical sciences optics microscopy
- medical and health sciences basic medicine physiology
- natural sciences biological sciences genetics RNA
- natural sciences chemical sciences organic chemistry amines
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-12
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IRG - Marie Curie actions-International re-integration grants
Coordinator
BUCURESTI
Romania
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.