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Engineered Nanoparticle Impact on Aquatic Environments: Structure, Activity and Toxicology

Objective

The use of engineered nanoparticles in cosmetics, pharmaceuticals, sensors and many other commercial applications has been growing exponentially over the past decade. EU and Member State’s research into the environmental impact of these materials, particularly in aquatic systems, is at an early stage. ENNSATOX addresses this deficit through a, comprehensive investigation relating the structure and functionality of well characterised engineered nanoparticles to their biological activity in environmental aquatic systems. An integrated approach will assess the activity of the particles in a series of biological models of increasing complexity. Parallel environmental studies will take place on the behaviour of the nanoparticles in natural waters and how they modify the particles' chemical reactivity, physical form and biological activity. An integrated theoretical model will be developed describing the environmental system as a series of biological compartments where particles transport between a) compartments by advection-diffusion and b) between phases by a transfer function. Following optimisation of the transfer functions a generic predictive model will be derived for the environmental impact of each class of nanoparticle in aqueous systems. A generalised understanding of the dependence of the nanoparticle biological activity on its structure and functionality will be obtained including the role and interaction of the biological membranes within organisms. ENNSATOX will generate: 1) exploitable IP (devices and ecotoxicology predictive software package); 2) set of standard protocols for assay of nanoparticle biological activity which can be later accredited; 3) global dissemination of results; 4) creation of an EU laboratory service; 5) tools and data to inform EU Regulation and the EC’s code of conduct for responsible nanosciences and nanotechnologies research, ftp://ftp.cordis.europa.eu/pub/nanotechnology/docs/nanocode-recommendation-pe0894c08424_en.pdf.

Field of science

  • /natural sciences/chemical sciences/electrochemistry/bioelectrochemistry/electroporation
  • /natural sciences/computer and information sciences/software
  • /engineering and technology/nanotechnology
  • /natural sciences/physical sciences/theoretical physics/particles
  • /social sciences/social and economic geography/transport
  • /medical and health sciences/basic medicine/toxicology

Call for proposal

FP7-NMP-2008-SMALL-2
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

UNIVERSITY OF LEEDS
Address
Woodhouse Lane
LS2 9JT Leeds
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 913 309,52
Administrative Contact
Karen Steenson (Dr.)

Participants (6)

WAGENINGEN UNIVERSITY
Netherlands
EU contribution
€ 602 812,48
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mieke Kleijn (Dr.)
UNIVERSITEIT ANTWERPEN
Belgium
EU contribution
€ 463 952,40
Address
Prinsstraat 13
2000 Antwerpen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Anne Adams (Ms.)
STAZIONE ZOOLOGICA ANTON DOHRN
Italy
EU contribution
€ 303 480
Address
Villa Comunale
80121 Napoli
Activity type
Research Organisations
Administrative Contact
Giosuè Zurzolo (Mr.)
UNIVERSIDAD DE LLEIDA
Spain
EU contribution
€ 237 028,80
Address
Placa Victor Siurana 1 1
25003 Lleida
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Josep M. Sentis Sune (Mr.)
Society of Environmental Toxicology and Chemistry - Europe VZW
Belgium
EU contribution
€ 88 638,40
Address
Avenue De La Toison D'or 67
B-1060 Brussels
Activity type
Research Organisations
Administrative Contact
Katrien Arijs (Ms.)
MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM
United Kingdom
EU contribution
€ 207 278,40
Address
Citadel Hill The Laboratory
PL1 2PB Plymouth
Activity type
Research Organisations
Administrative Contact
Nola Venton (Ms.)