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Integrated Chemical synthesis and Screening in patient Cells

Objective

The ICSC project is a “Research for SMEs” focused research project that is to develop an integrated high throughput chemical synthesis and cell-based screening platform for the development of efficacious novel drug candidates without the need for chemical nor cell biological infrastructure. The technology will put early drug discovery in the hands of institutions that have a comprehensive knowledge of disease mechanisms and management of patients. The technological core of the ICSC project is a newly developed high-throughput drug discovery technology ChemoCellomics®, which integrates chemical synthesis and high throughput cell-based screening in a polymer-based format. The ChemoCellomics® technology will in the ICSC project be converted to a bench-top technology where optically encoded micro carriers will hold chemical library member and patient cells. The structural identity of the chemical library member is optically encoded in each carrier. It is expected that the ICSC technology will have a major impact on multiple areas within life sciences in particular drug discovery. Early drug screening and development of drug candidates including synthesis of chemical libraries and high throughput cell-based screening have previously been reserved pharmaceutical- and major biotechnology companies with comprehensive chemistry- and cell biological infrastructure. The philosophy behind the development of the ICSC technology is to provide institutions (hospitals, academia and small biotechnology companies) possessing detailed knowledge about disease mechanisms and patient treatment, with a capability to exploit this knowledge in early drug discovery.

Call for proposal

FP7-SME-2008-1
See other projects for this call

Coordinator

2CUREX A/S
Address
Fruebjergvej 3
2100 Kobenhavn
Denmark
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 604 000
Administrative Contact
Ole Thastrup (Dr.)

Participants (5)

MICROLIQUID SL
Spain
EU contribution
€ 235 500
Address
Avenida Uribarri 19-1 Saiolan
20500 Arrasate Mondragon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Borja Barredo (Dr.)
PROTEIN LABORATORIES REHOVOT LTD
Israel
EU contribution
€ 206 100
Address
Hagefen 11
76349 Rehovot
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Arieh Gertler (Prof.)
UNIVERSITY OF SOUTHAMPTON
United Kingdom
EU contribution
€ 4 000
Address
Highfield
SO17 1BJ Southampton
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mills Joan (Ms.)
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 3 200
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Conni Holbaek (Ms.)
REGION HOVEDSTADEN
Denmark
EU contribution
€ 3 200
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Steen Werner Hansen (Prof.)