Objective Lassa fever is a zoonotic disease caused by Lassa virus. The disease is endemic in West Africa. Hemorrhagic courses of Lassa fever are associated with high mortality. It is estimated that 100,000 to 500,000 infections occur each year because of transmission of Lassa virus from its rodent reservoir (Mastomys natalensis) to human. Rodent control measures could reduce the risk of rodent-human transmission. However, the dynamics of virus-rodent interaction is poorly understood. This information is crucial to design efficient and cost-effective rodent control measures. Therefore, objective of the research project is to enhance knowledge on rodent ecology and molecular taxonomy as well as on microphylogeny, transmission, and persistence pattern of the virus in the rodent population. A second objective is the improvement of laboratory skills of the applicant in the area of virology and molecular biology to facilitate a multidisciplinary Lassa virus research linking rodent ecology, molecular epidemiology, diagnostics, and virology. Fields of science social sciencessociologydemographymortalitynatural sciencesbiological sciencesmicrobiologyvirologynatural sciencesbiological sciencesecologymedical and health scienceshealth sciencespublic healthepidemiologyzoonosisnatural sciencesbiological sciencesmolecular biology Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-IEF-2008 - Marie Curie Action: "Intra-European Fellowships for Career Development" Call for proposal FP7-PEOPLE-IEF-2008 See other projects for this call Funding Scheme MC-IEF - Intra-European Fellowships (IEF) Coordinator BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN EU contribution € 230 288,97 Address BERNHARD NOCHT STRASSE 74 20359 Hamburg Germany See on map Region Hamburg Hamburg Hamburg Activity type Research Organisations Administrative Contact Stephan Günther (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
