Applications of Organocatalysis to Supramolecular Chemistry

Objective

The development of new synthetic strategies that allow increasingly rapid access to structural complexity and new molecular architectures remains one of the fundamental challenges for the chemical sciences. Over the last eight years, organocatalysis—particularly that associated with chiral secondary amines—has become an established and powerful synthetic tool for the chemo- and enantioselective functionalisation of carbonyl compounds, and has already had significant impact in the synthesis of natural products, intermediates for pharmaceuticals and other structurally complex biologically active compounds. The aim of this proposal is to develop and investigate for the first time the application of organocatalytic chemistry to complex structure synthesis in supramolecular chemistry. In particular, I intend to investigate the utility of these reactions in facilitating the first organocatalytic ‘active template’ synthesis of rotaxanes.

Fields of science

• medical and health sciences › basic medicine › pharmacology and pharmacy › pharmaceutical drugs
• natural sciences › chemical sciences › organic chemistry › amines

Keywords

• Molecular chemistry
• Organic chemistry
• Supramolecular Chemistry

Programme(s)

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Topic(s)

• FP7-PEOPLE-IEF-2008 - Marie Curie Action: "Intra-European Fellowships for Career Development"

Call for proposal

FP7-PEOPLE-IEF-2008
See other projects for this call

Funding Scheme

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE UNIVERSITY OF EDINBURGH

Address

Old College, South Bridge
EH8 9YL Edinburgh
United Kingdom

Activity type

Higher or Secondary Education Establishments

Administrative Contact

Angela Noble (Ms.)

Links

EU contribution

€ 172 434,64