Objective The focus of my research project is the development of new solid-state Nuclear Magnetic Resonance (NMR) methodologies that allow the determination of the structure of solid or semi-solid samples. Materials of this type are central to many interesting biophysical questions but, because they are typically insoluble and non-crystalline, they are not amenable to structure determination by traditional biophysical techniques such as solution-state NMR or single-crystal X-ray diffraction. They may also have complicated intermolecular interactions that are not easily probed by single-molecule studies. Solid-state NMR may prove particularly informative for the study of these systems because of its inherent atomic resolution and its requirement for only local order. I plan to develop new NMR methods, based on Switched Angle Spinning, to study these kinds of materials. The group of Prof. M. H. Levitt at the University of Southampton is highly recognized in the scientific community for the development of a theory that allows NMR experiments useful to specific purposes, as structure determination, to be designed using symmetry principles. Taking advantage of the knowledge of the host organization, I plan to apply this approach to the development of new experiments allowing the measurements of either homonuclear and heteronuclear dipolar couplings for selected couples of nuclei, giving access to very detailed structural details. Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-IEF-2008 - Marie Curie Action: "Intra-European Fellowships for Career Development" Call for proposal FP7-PEOPLE-IEF-2008 See other projects for this call Funding Scheme MC-IEF - Intra-European Fellowships (IEF) Coordinator UNIVERSITE D'AIX MARSEILLE Address Boulevard charles livon 58 le pharo 13284 Marseille France See on map Region Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône Activity type Higher or Secondary Education Establishments Administrative Contact Céline Damon (Ms.) Links Contact the organisation Opens in new window EU contribution € 164 310,52 Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITE DE PROVENCE Participation ended France EU contribution € 0,00 Address 3 place victor hugo 13331 Marseille See on map Activity type Higher or Secondary Education Establishments Administrative Contact Audrey Janssens (Ms.) Links Contact the organisation Opens in new window
