Objective
This project aims to follow the fate of three groups of aquatic bioactive compound from raw material to active cellular site; long-chain omega-3 polyunsaturated fatty acids (omega-3 PUFA), fish peptides and seaweed polyphenols. The focus is to study if there are bioactivity losses prior to ingestion (i.e. during storage in a food product) or during gastrointestinal (GI) digestion and investigate wether there may be potential positive/deleterious effects of the compounds after digestion. This work will be done in collaboration with Chalmers University and University of Florida, USA. Omega-3 PUFA are highly prone to oxidation. No research has been done to clarify their oxidation under GI passage, which may be highly pro-oxidative. Few studies have linked putative ex vivo PUFA oxidation in food products with changes in bioactive responses after digestion and cellular uptake. Also, interaction between the PUFA and peptides/polyphenols in this chain of events is a novel research focus. The impact of dosage and food matrix formulation for the interplay addressed will be of special importance in development of safe functional food products with aquati bioactives. The project is divided into four work packages: (1) Production/analysis of three bioactive compounds, (2) Stability of bioactives alone or in a food model, (3) GI-oxidation/antioxidation of omega-3 PUFA, peptides and polyphenols using static/dynamic models, and (4) Effect of bioactives digests on antioxidative/oxidative and anti-inflammatory responses in cells. The outcomes will aid toxicologists to develop biomarkers and validate safety of bioactives, nutritionists to design dietary guidelines, food industry to optimizing functional food product formulations and the public to better understanding how to eat to remain healthy.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences chemical sciences electrochemistry electrolysis
- natural sciences biological sciences biochemistry biomolecules lipids
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IRG-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
113 Reykjavik
Iceland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.