There is substantial interest in the construction of multiporphyrin assemblies, which can mimic naturally occurring multichromophore aggregates, thus generating potential electron- and/or energy-transfer molecular devices for advanced technological tasks. Three-dimensional macrocyclic oligomers of metalloporphyrins are also being actively investigated as host molecules for homogeneous catalysis and selective molecular recognition that can result from the specific geometry of cavities defined by porphyrin planes.
The study of dynamic combinatorial libraries (DCLs), and selective amplification of species complementary to templates, is a rapidly growing field of research. In the recent years the DCLs approach has become one of the more useful tools available to supramolecular chemists to selectively amplify and isolate, from a mixture at thermodynamic equilibrium, novel, and otherwise difficult to obtain, functional three-dimensional structures of nanoscopic dimensions. The present project is aimed at the design and synthesis of new porphyrin building blocks bearing suitable functionalities to construct dynamic libraries (DCLs) of multiporphyrin assemblies, with the specific objective of amplifying and isolating novel versatile three-dimensional architectures in high yield.
The final multiporphyrin cage-type adducts will be investigated for molecular recognition, selective catalysis and photo-induced applications. Dynamic synthesis of porphyrin water-soluble superstructures, such as catenanes and rotaxanes, will also be addressed.
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