Objective
The objective of the project is to map the functional activation of cortical substructures in the human visual cortex in vivo for the first time. This shall be achieved by utilizing recent advances in MR imaging technology, namely the use of an ultra-high magnetic field strength (7 Tesla) to increase functional contrast and a parallel imaging approach to speed up data acquisition, in combination with a new functional magnetic resonance imaging method susceptible to venous vessels, dubbed functional MR venography (fMRV). The training aspects involve a very complex methodological part and a highly demanding functional neuro-imaging part. The methodological training aims to accumulate and broaden the expertise regarding these novel promising MR technologies (i.e. parallel imaging at ultra-high field strengths) within the EU to keep up with the current technological forefront in this area. Training in the functional neuro-imaging part will focus on the primary visual cortex (V1) as much is known regarding its cortical architecture. The aim is to demonstrate that the proposed method is capable of mapping functional activation in distinct cortical layers - this shall be demonstrated using spatial averaging of cortical profiles perpendicular to the cortical surface; success in this part would demonstrate for the first time that fMRV at 7 Tesla is able to determine whether activated cortex is primarily receiving input (layer IV) or generating output (layer II) or both. Studies of brain networks would benefit immensely from such a direct mapping of in- and output. We also aim to map blobs and inter-blobs which are even smaller intra-cortical subunits in cortical layers II-III of V1 showing different metabolic demand and vascular architecture. Both parts involve complex image processing, i.e. segmentation of MR data sets and subsequent cortical flattening as well as analyzing the fMRV data sets in the temporal domain.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-5
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.