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The Integrated Neurobiology of Food Intake, Addiction and Stress

Objective

NeuroFAST is a multidisciplinary project, involving ten teams from seven countries, to explore the neurobiology of addiction and eating behaviour and the complex socio-psychological forces that can lead to its dysregulation. These forces include dietary components (including highly palatable foods and alcohol), some of which may have addictive properties, but also cultural and social pressures, everyday stressors, and family-genetic influences on these. The project will provide new data from human studies, including human nutritional studies, that is needed to inform health policy initiatives. This will be underpinned by state-of-the art mechanistic research to establish a solid scientific basis for this advice. The European added value lies in building up the necessary critical mass in several fields of expertise: psychology, epidemiology, human genetics related to eating disorders, human nutrition, eating and addictive behaviour disorders, endocrinology, human brain imaging, together with studies of the basic mechanisms of eating behaviour and addiction, (neuro)endocrine regulators, stress, opiate dependence, and cannabinoid actions. To provide scientific support for European public health policies, a focus will be on a socio-psychological analysis of determinants of food addiction and substance abuse, and of how risk factors like stress in the workplace are driving addictive behaviour. We will establish an evidence base for inter-relationships, linking eating disorder research with obesity research, stress research and addiction research, and involving studies of selected individual food components using novel designed foods with controlled components. In summary, we will use a synergistic combination of controlled laboratory studies, characterization of patient groups, and examination of real-world scenarios based on epidemiological community samples that will be relevant to policy development.

Field of science

  • /medical and health sciences/health sciences/public and environmental health
  • /medical and health sciences/basic medicine/medical genetics
  • /medical and health sciences/clinical medicine/endocrinology
  • /natural sciences/biological sciences/genetics and heredity
  • /medical and health sciences/health sciences/substance abuse
  • /medical and health sciences/health sciences/epidemiology
  • /social sciences/psychology
  • /natural sciences/biological sciences/neurobiology
  • /medical and health sciences/health sciences/nutrition

Call for proposal

FP7-KBBE-2009-3
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

GOETEBORGS UNIVERSITET
Address
Vasaparken
405 30 Goeteborg
Sweden
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 606 120
Administrative Contact
Emilia Rung (Dr.)

Participants (12)

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 591 800
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Roger Adan (Prof.)
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
EU contribution
€ 217 790
Address
Via Zamboni 33
40126 Bologna
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Uberto Pagotto (Dr.)
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
United Kingdom
EU contribution
€ 924 079
Address
King's College Regent Walk
AB24 3FX Aberdeen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ian Tough (Mr.)
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 245 800
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Keith Cann (Mr.)
UNIVERSITAETSKLINIKUM ESSEN
Germany
EU contribution
€ 507 470
Address
Hufelandstrasse 55
45147 Essen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
George Sebastian (Mr.)
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 662 345
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Angela Noble (Ms.)
TECHNISCHE UNIVERSITAET DRESDEN
Germany
EU contribution
€ 159 100
Address
Helmholtzstrasse 10
01069 Dresden
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lars Henning (Dr.)
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Spain
EU contribution
€ 207 780
Address
Colexio De San Xerome Praza Do Obradoiro S/n
15782 Santiago De Compostela
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Fernando Sedano Arnaez (Dr.)
KIRSERLETI ORVOSTUDOMANYI KUTATOINTEZET
Hungary
EU contribution
€ 227 800
Address
Szigony Utca 43
1083 Budapest
Activity type
Research Organisations
Administrative Contact
Zsolt Liposits (Prof.)
NIZO FOOD RESEARCH BV
Netherlands
EU contribution
€ 292 100
Address
Kernhemseweg 2
6718 ZB Ede Gld
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Joost Overduin (Dr.)
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
EU contribution
€ 307 800
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
Administrative Contact
Fausto Pedrazzini (Dr.)
FONDAZIONE TOSCANA GABRIELE MONASTERIO PER LA RICERCA MEDICA E DI SANITA PUBBLICA
Italy
EU contribution
€ 50 000
Address
Via Trieste 41
56126 Pisa
Activity type
Research Organisations
Administrative Contact
Luciano Ciucci (Dr.)