Objectif The consortium will discover and carry to the stage of development candidates, plant derived small molecules with potential as new cosmetic and agrochemical agents. These compounds will derive from plants originating from major biodiversity hotspots in Europe, Africa, Latin America, and the Asia-Pacific region. The starting point of the project will be a diversity-oriented natural product library of 500 compounds from the existing compound repositories of three project partners. Screening of this compound library in assay panels for agrochemical (antifungal, herbicidal, insecticidal) and cosmetic properties (UV-protection, anti-aging, anti-hyperpigmentation) will rapidly identify promising scaffolds. This knowledge will serve as entry points for a chemotaxonomy and chemodiversity oriented collection of plants which are thought to contain structural variants and decorations of these scaffolds. A liquid library of 3600 extracts will be generated and screened. Stringent prioritization and profiling procedures will generate 100 compounds as focused sub-libraries around the privileged scaffolds. A state-of-the-art technology platform for miniaturized natural product discovery will be used for the purpose. Evaluation of these sub-libraries will lead to 30 compounds which will undergo advanced testing to qualify 5 compounds as development candidates for novel agrochemical and/or cosmetic agents with new or improved properties over existing active ingredients. An additional outcome of the project will be an extract library with a unprecedented level of associated spectroscopic information and metadata, to be used for future purposes. The high-caliber consortium brings together international leaders in small molecule natural products, bioprospection, leading industries in agrochemistry, cosmetics, and spectroscopic data management and analysis. Champ scientifique sciences naturellessciences biologiquesécologieécosystème Programme(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Thème(s) KBBE-2009-3-1-04 - Prospecting for novel plant-produced compounds Appel à propositions FP7-KBBE-2009-3 Voir d’autres projets de cet appel Régime de financement CP-FP - Small or medium-scale focused research project Coordinateur ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Adresse 6 christou lada str 10561 Athina Grèce Voir sur la carte Région Αττική Aττική Κεντρικός Τομέας Αθηνών Type d’activité Higher or Secondary Education Establishments Contact administratif Efi Kafentzi (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Contribution de l’UE € 706 753,40 Participants (8) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire UNIVERSITAT BASEL Suisse Contribution de l’UE € 378 045,00 Adresse Petersplatz 1 4051 Basel Voir sur la carte Région Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Type d’activité Higher or Secondary Education Establishments Contact administratif Matthias Hamburger (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France Contribution de l’UE € 665 301,60 Adresse Rue michel ange 3 75794 Paris Voir sur la carte Région Ile-de-France Ile-de-France Paris Type d’activité Research Organisations Contact administratif Véronique Debisschop (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window UNIVERSIDAD DE PANAMA Panama Contribution de l’UE € 80 680,00 Adresse Calle manuel espinosa batista sn 0824 Panama Voir sur la carte Type d’activité Higher or Secondary Education Establishments Contact administratif Betty Ann Rowe De Catsambanis (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH Afrique du Sud Contribution de l’UE € 210 243,00 Adresse Meiring naude road, brummeria 46 0001 Pretoria Voir sur la carte Type d’activité Research Organisations Contact administratif Sandy Farnworth (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window BASF SE Allemagne Contribution de l’UE € 308 690,00 Adresse Carl bosch strasse 38 67063 Ludwigshafen am rhein Voir sur la carte Région Rheinland-Pfalz Rheinhessen-Pfalz Ludwigshafen am Rhein, Kreisfreie Stadt Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Michael Roeper (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window KORRES S.A. NATURAL PRODUCTS (KORRES ANONIMI ETERIA FYSIKA PROIONTA) Grèce Contribution de l’UE € 281 120,00 Adresse 57th km athens-lamia national road 32011 Inofyta Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Dimitris Vidakis (Mr.) Liens Contacter l’organisation Opens in new window BRUKER BIOSPIN GMBH Allemagne Contribution de l’UE € 172 800,00 Adresse Rudolf-plank-strasse 23 76275 Ettlingen Voir sur la carte Région Baden-Württemberg Karlsruhe Karlsruhe, Landkreis Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Eberhard Eckert (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" Grèce Contribution de l’UE € 100 000,00 Adresse End of patriarchou grigoriou e and 27 neapoleos street 15341 Agia paraskevi Voir sur la carte Région Αττική Aττική Βόρειος Τομέας Αθηνών Type d’activité Research Organisations Contact administratif Marina Fontara Liens Contacter l’organisation Opens in new window Site web Opens in new window
