Objective
The scientific aim of InduVir is to produce novel comparative information on the generation, maintenance and characteristics of iPS cells in mouse and on their differentiation towards different, especially cardiac lineages. In InduVir we are aiming to develop a novel system, by using removable transposons and polycistronic, deletable lentiviruses and therefore significantly reduce the risk of malignant transformations associated with conventional iPS technologies. Technical focus will be developing a novel and potentially patentable technology in Europe for reprogramming somatic cells to an embryonic state, which have a excellent potential for future cell based therapy. InduVir will also develop methods for targeted differentiation of the iPS cells to cardiac cells. We expect to get novel information on pathways and transcriptional networks that regulate differentiation and lineage specification. The differentiated cardiac tissues would provide superior tools for pharmacological studies or high-throughput screening. IPS technology has the great potential to generate patient and disease specific stem cells and derivates, yet it lacks many of the technical, ethical and legal issues associated with human ES cell research including therapeutic cloning.The information generated by these studies will contribute to stem cell therapy and modern regenerative medicine.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences medical biotechnology genetic engineering gene therapy
- medical and health sciences medical biotechnology cells technologies stem cells
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-RG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
2100 Goedoello
Hungary
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.