Objective
The aim of this project is to develop a non-invasive diagnostic tool for medical applications, such as the early diagnosis of diseases, by real-time analysis of trace gas concentrations in human breath. Presently, early detection requires very expensive invasive tests, e.g. biopsy, endoscopy and x-rays that may be painful and potentially harmful. The challenge to modern medicine is to develop cost-effective and non-invasive tests for early diagnosis. We propose to develop and apply a novel type of laser-based analytical instrument, the optical nose, for rapid screening of human breath, in order to identify in real time the specific markers related to various diseases. We shall focus on chronic obstructive pulmonary diseases, lung cancer and colorectal cancer, as lead to get a "proof of concept". The consortium will perform research on the currently most promising trace gas analysis methods based on advanced mid-IR laser sources, optical parametric oscillators (OPOs), in combination with ultra-sensitive spectroscopic detection methods. By exploiting the latest solid-state laser and optical fibre technology, the capabilities of existing OPOs will be considerably extended and matching detection methods will be developed to retrieve and computer-analyse trace gas concentration data within only seconds. The laser-based analytical instrument will operate in the 2.5-10 mm wavelength range with maximum coverage of the molecular fingerprint region and a superior wavelength agility (tens of thousands of distinct wavelengths per second). This enables rapid and accurate medical examination of human breath, as required for building a database connecting the spectroscopic data of the breath analysis with medical evidence.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences databases
- medical and health sciences clinical medicine oncology lung cancer
- medical and health sciences clinical medicine oncology colorectal cancer
- natural sciences physical sciences optics fibre optics
- natural sciences physical sciences optics laser physics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-NEST-A
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NIJMEGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.