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Content archived on 2024-06-16

Rational design of long-wavelength chromo- and fluorogenic chemosensors and composite materials for ionic analytes

Objective

In optical sensing of chemical species, the performance of a sensor strongly depends on selectivity, sensitivity and the suitability of the wavelength range of communication. In many environmental and biochemical applications however the matrix can autofluoresce or absorb the light used for probing the sensor and response.

A suitable way to circumvent such interferences and to improve the sensor and specificity is to operate in the red-visible or near infrared (NIR) spectral region, preferably with a sensitive and versatile method such as fluorometry. Biological matrices are optically silent above 650 nm. However, despite the rapid growth of the field of chemosensor research lately, examples of molecular NIR probes and actual sensor materials a re still very limited.

The proposal aims to develop, characterize and test new functional molecules and composite sensor materials for the optical detection of a charged inorganic and a group of organic analytes of biological importance in these long-wave spectral ranges. To achieve these objectives, first, rational molecular design employing theoretical and empirical methods is used to generate suitable dye platforms with integrated receptor units that respond to a guest by specific changes in their spectroscopic signal.

After synthesis and testing, the molecular probes are then incorporated into nanoscopic materials. The latter step allows tuning the selectivity and promises to obtain composite, organic-inorganic, sensor materials with tailor-made performance in an analytically advantageous spectral range.

The proposal addresses many issues of FP6 and NMP Priority Areas 3.4.2.1-2 and 3.4.2.3-1 and thus lies in a highly topical research field. Its general scientific and technological work is assumed to generate new ideas on advanced chemosensor design and promises to achieve the development of innovative optical materials in nanotechnology.

Fields of science (EuroSciVoc)

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Keywords

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Topic(s)

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Call for proposal

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FP6-2004-MOBILITY-5
See other projects for this call

Funding Scheme

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EIF - Marie Curie actions-Intra-European Fellowships

Coordinator

BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG
EU contribution
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Total cost

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