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Corline Heparin Technology - Enabling Regenerative Medicine

Objective

Regenerative Medicine (use of cells and tissue to replace or heal impaired functions in the body, RM) is one of the fastest growing areas in today’s medicine, and has the potential to offer treatment to patients with diseases that are currently untreatable. In many new areas of RM there is however a need to improve the outcome of RM concepts and technologies for it to become a viable option to traditional medicine, or even to motivate the risk of clinical trials and treatments. One of the main problems in several RM areas is that a large portion of the cell and tissue material is lost or made dysfunctional during and shortly after transplantation and that the transplant does not connect to the host tissue as a functional new graft. The specific scientific objective of this project is twofold: 1) to clinically test and prove that Corline Heparin Surfaces (CHS) can be used to protect donated human insulin producing cells that are transplanted to severe cases of Diabetes Type 1 patients, and 2) to broaden the application of the technology and show that the CHS technology can function as a protective and revascularization promoting technology for other Regenerative Medicine areas. The goal is to show CHS’s further applicability to Liver Cell therapy, Xeno transplantation of Islet of Langerhans and to Tissue Engineering In addition to the detailed scientific objective, this project has a specific technological objective. The technological objective of this project is to, in partnerships with the participating SMEs, improve European top grade clinical Regenerative Medicine products by combining them with the CHS technology, transferring the application knowledge and integrating the CHS technology into the partners’ cell and tissue production processes, and to set up a reliable sourcing chain with supply and production of reagents and tissue products to end-user.

Field of science

  • /medical and health sciences/medical biotechnology/tissue engineering
  • /medical and health sciences/clinical medicine/transplantation
  • /medical and health sciences/clinical medicine/endocrinology/diabetes
  • /social sciences/economics and business/economics/production economics

Call for proposal

FP7-SME-2010-1
See other projects for this call

Funding Scheme

BSG-SME - Research for SMEs

Coordinator

NORDICBLUE AB
Address
Kristinedalsvaegen 48
131 46 Nacka
Sweden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 84 000
Administrative Contact
Mats Wallnér (Mr.)

Participants (10)

Cytonet GmbH & Co. KG
Germany
EU contribution
€ 13 500
Address
Albert-ludwig-grimm-str. 20
69469 Weinheim
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lubomir Arseniev (Dr.)
BETA-CELL
Belgium
EU contribution
€ 250 500
Address
Researchpark Z.1. 310
1731 Zellik
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Sven Andréasson (Mr.)
Tissue Regenix Limited
United Kingdom
EU contribution
€ 231 000
Address
Innovation Way The Biocentre
Y0105 NY York
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Antony Odell (Dr.)
UPPSALA LANS LANDSTING
Sweden
EU contribution
€ 3 000
Address
Po Box 602
751 25 Uppsala
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Gunnar Tufveson (Prof.)
Stricent AB
Sweden
EU contribution
€ 3 000
Address
St Lars Vag 42
SE22270 Lund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jerker Ringström (Mr.)
MEDIZINISCHE HOCHSCHULE HANNOVER
Germany
EU contribution
€ 3 000
Address
Carl-neuberg-strasse 1
30625 Hannover
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Frank Dittrich (Mr.)
Aurigon Life Science GmbH
Germany
EU contribution
€ 3 000
Address
Bahnhofstrasse 9 - 15
D-82327 Tutzing
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gerhard Hager (Dr.)
VRIJE UNIVERSITEIT BRUSSEL
Belgium
EU contribution
€ 3 000
Address
Pleinlaan 2
1050 Brussel
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christel Hendriekcx (Dr.)
UNIVERSITY OF LEEDS
United Kingdom
EU contribution
€ 3 000
Address
Woodhouse Lane
LS2 9JT Leeds
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eileen Ingham (Prof.)
CORLINE BIOMEDICAL AB
Sweden
EU contribution
€ 538 500
Address
Lefflersgatan 5
754 50 Uppsala
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Henrik Nittmar (Dr.)