Objective
There is a strong need for new thermostable hydrolases with appropriate performance and/or novel functionalities that could provide huge savings in time, money and energy for industrial processes. The HotZyme project aims to identify such enzymes from hot terrestial environments, using metagenomic screening methods. New bioinfomatic tools will be developed to facilitate function prediction of genes from metagenomes that show low or no sequence homology to enzymes of known function. A range of high-throughput screening technologies will be employed to identify novel hydrolases. The consortium is composed of 13 partners from 10 European countries plus one partner from USA. The strong expertise in Microbiology, Moleculary Biology, Biochemistry, Biophysics, Geochemistry, Nanotechnology and Bioinformatics from our partners will be integrated in the project to ensure the fulfilment of the proposed tasks. Importantly, the five industrial partners, including three SMEs, will seek to commercialize the project results, thus ensuring a European wide impact, post project.
Field of science
- /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes
Call for proposal
FP7-KBBE-2010-4
See other projects for this call
Funding Scheme
CP-IP - Large-scale integrating projectCoordinator
1165 Kobenhavn
Denmark
Participants (12)
1171 PK Badhoevedorp
59717 Bozeman
N-0855 Oslo
117312 Moskva
2880 Bagsvaerd
6708 PB Wageningen
EX4 4QJ Exeter
9470 Buchs
00185 Roma
15780 Athina
45141 Essen
30500 Binyamina
