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The Cerebellum in visual-spatial orientation (CERVISO) is an inter-disciplinary, exchange program in which original and innovative research methods are used to investigate the role of the cerebellum and its connections with other subcortical and cortical structures, in the optimization of motor control and spatial orientation. Toward this objective we have identified patterns of cerebellar and basal ganglia functions using the saccadic eye movement model. We were particularly interested in understanding how the cerebellum and other connected brain areas drive eye movements during visual spatial exploration and in modelling some cerebellar and basal ganglia functions during gaze orienting. Beside motor control , during the course of the project, non motor aspects of visual perception, sensory-motor coupling and visual exploration including attention, planning, memory and decision making were evaluated. Of particular interest and innovation was the study of visual spatial exploration and visual perception during saccadic eye movements in patients with cerebellar and basal ganglia damage and patients with rare neurodegenerative diseases. At the same time a special effort was directed toward the realization of new methods for the analysis of gaze during tasks of visual sequencing, multisensory integration and dual decision making in neuroeconomic tasks. We also evaluated some effects of magnetic fields on vestibular system and the possible use of magnetic coils in the rehabilitation of vestibular diseases. The impact of this research was to provide further instruments for understanding and modelling neural substrate of brain functions during visual spatial exploration, with implications for diagnosis, and rehabilitation of patients with movement disorders and perceptual disabilities. The proposal has been implemented combining the efforts of three European groups and four USA groups. Another important impact of this project was the development of a group of researchers well trained in technical, procedural and scientific aspects of the study. This has been obtained thanks to the participation of experienced organizations. Moreover this proposal facilitated the transfer of knowledge among researchers with experience in different scientific fields and the study of rare genetic diseases clustered in specific regions. In addiction promoting innovative approaches to neurosciences, this project is supporting the translation of basic research into concrete applications such as the rehabilitation of motor and attentive problems. The translational approach adopted in CERVISO is testified by the dissemination of our scientific production in different fields of research such as Biophysic, Bioengineering, Neurosciences, Clinical Neurology, Rare Diseases Diagnostic Tools, Cognitive Rehabilitation. The European groups include the INSERM team of Neurologists and Neuropsychologists from Paris (France); a group of Neurologists and Bioengineering from the University of Siena (Italy); a group of Physicists from University of Iasi (Romania). The USA Groups are composed by a team of Bioengineering and Neuroscientists from Baltimore, and NEI Bethesda, and by a group of Neuroscientists and Bioengineers from Cleveland and Phoenix. This exchange program results from previous scientific collaboration among these groups and has been projected for a sustainable long-term cooperation. The project has been selected for a Grant by the Local Institution (Regione Toscana) of Ministry for Research and Development that specifically support the application to this call.". In conclusion, with CERVISO project we are aware that concretely are contributing to the ERA core objective to build a “knowledge society” thorough a “knowledge triangle” (higher education, research, innovation) and free circulation of knowledge