Objective
In the framework of studies of the organization and evolution of the bread wheat genome, the host team has developed a large project aiming to characterize its largest chromosome, 3B, at the molecular level. A physical map of this giant chromosome (about the size of the soybean genome) was established in 2008 (Paux et al., 2008). Recently, in a pilot study prior to the complete chromosome sequencing (3BSEQ project), the host group produced and analyzed precisely 18 Mb of contiguous sequences representing the first large sample sequences available for the hexaploid wheat genome. The results showed that about 50% of the genes and pseudogenes identified in wheat are not collinear with the other grass genomes raising several questions about their origin, fate and expression in the wheat genome.
The objectives of this project are to select a number of non collinear genes in different structural contexts and (i) determine whether these genes originate from interchromosomal duplications of genes ancestrally present at distant loci, (ii) investigate the molecular mechanisms and evolutionary forces involved in the shuffling of the gene content, including transposable elements, and (iii) analyze their expression patterns relative to collinear genes through qRT-PCR experiments and analysis of RNA Seq data that will be produced in the 3BSEQ project on 15 different RNA samples. We will investigate the molecular evolution of their sequences in a hexaploid context where homoeologous and paralogous gene copies are maintained.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences evolutionary biology
- natural sciences biological sciences genetics RNA
- natural sciences biological sciences genetics chromosomes
- natural sciences biological sciences genetics genomes
- natural sciences biological sciences molecular biology molecular evolution
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.