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Content archived on 2024-06-18

Assessment of the hazard and opportunities of using carbon nanotubes as a new nanocarrier for drug delivery in neural tissue

Objective

"While neurodegenerative disorders and brain cancers increase in the population, current therapies have shown their limits. But thanks to recent advancements in nanosciences and nanotechnologies, new therapeutic opportunities are offered based on the development of nanoscale drug delivery systems. Among those, carbon nanotubes (CNT) have shown promising applications for therapy of a broad range of diseases because of their highly tunable abilities to transport different molecules and to penetrate cells. In this multidisciplinary project, we propose to use chemically functionalised CNT (f-CNT) as drug delivery systems for brain disease. However, since the knowledge concerning the interaction of CNT and the brain parenchyma is poor, the main goals of the project will be to define: (i) the potential hazard of using f-CNT in the brain and (ii) the pharmaceutical opportunities that these nanocarrier systems could offer. Our overall objective will be to identify critical parameters for the design/engineering of safe and effective carbon nanotubes based drug nanovectors for brain disease, with a special focus on the CNT surface functionalization. We will use both in vitro and in vivo studies to adresses these different questions."

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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FP7-PEOPLE-2010-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

UNIVERSITY COLLEGE LONDON
EU contribution
€ 199 549,60
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (1)

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