Objective Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role in the drive towards personalised medicine remains uncertain.Based on harmonised and standardised European population cohorts we have built significant research collaboration, expertise and infrastructure in the EU. We will apply highly innovative SME-driven technologies and perform large-scale biomarker determination to assess the predictive value of existing and emerging biomarkers.Selection of emerging biomarkers will be based on integrated cutting-edge quantitative proteomic, transcriptomic, metabolomic, and miRNomic datasets established by private and public consortium members that will be disclosed to this consortium. Existing biomarkers will be selected based on non-redundancy and their association with cardiovascular risk and phenotypes. After SME-guided development of innovative assay systems biomarkers will be tested and validated in a stepwise fashion among European populations in primary and secondary prevention. In addition to their impact on risk prediction, their association with lifestyle determinants and cardiovascular phenotypes assessed by ultrasound and MRI technique will be evaluated.We will establish a BiomarCaRE panel which leads to improved disease prediction among different European populations. International collaborations with world-class clinical trial investigators will add data on the interaction of the BiomarCaRE panel with risk-lowering medication and lifestyle changes. The outcome of SME-driven technology development and clinical validation will undergo a medical technology assessment. The determination of cost-effectiveness will guide further clinical evaluation. These studies will reveal new methods of improved cardiovascular risk estimation and will open the path towards personalised medicine. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsmedical and health sciencesclinical medicinecardiologycardiovascular diseasesmedical and health scienceshealth sciencespersonalized medicinenatural sciencesphysical sciencesacousticsultrasound Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2011.2.4.2-2 - Evaluation and validation studies of clinically useful biomarkers in prevention and management of cardiovascular diseases Call for proposal FP7-HEALTH-2011-two-stage See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF Address Martinistrasse 52 20251 Hamburg Germany See on map Region Hamburg Hamburg Hamburg Activity type Higher or Secondary Education Establishments Administrative Contact Tanja Zeller (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 1 255 925,00 Participants (29) Sort alphabetically Sort by EU Contribution Expand all Collapse all TERVEYDEN JA HYVINVOINNIN LAITOS Finland EU contribution € 737 440,00 Address Mannerheimintie 166 00271 Helsinki See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Research Organisations Administrative Contact Kari Kuulasmaa (Prof.) Links Contact the organisation Opens in new window Website Opens in new window CAVADIS BV Netherlands EU contribution € 867 880,00 Address Catharijnesingel 52 3511 GC Utrecht See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Heico Breek (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAIR MEDISCH CENTRUM UTRECHT Netherlands EU contribution € 105 780,00 Address Heidelberglaan 100 3584 CX Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Administrative Contact Gerard Pasterkamp (Prof.) Links Contact the organisation Opens in new window Website Opens in new window HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Germany EU contribution € 52 320,00 Address Ingolstadter landstrasse 1 85764 Neuherberg See on map Region Bayern Oberbayern München, Landkreis Activity type Research Organisations Administrative Contact Jürgen Ertel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window BIOCRATES LIFE SCIENCES AG Austria EU contribution € 372 560,00 Address Eduard bodem gasse 8 1 stock 6020 Innsbruck See on map Region Westösterreich Tirol Innsbruck Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Markus Speiser (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAET zu LUEBECK Germany EU contribution € 266 700,00 Address Ratzeburger allee 160 23562 Lubeck See on map Region Schleswig-Holstein Schleswig-Holstein Lübeck, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Gabriele Schatton Links Contact the organisation Opens in new window Website Opens in new window UMIT TIROL - PRIVATE UNIVERSITAT FUR GESUNDHEITSWISSENSCHAFTEN UND TECHNOLOGIE GMBH Austria EU contribution € 148 080,00 Address Eduard wallnoefer zentrum 1 6060 Hall in tyrol See on map Region Westösterreich Tirol Innsbruck Activity type Higher or Secondary Education Establishments Administrative Contact Petra Schnell-Inderst (Dr.) Links Contact the organisation Opens in new window MEDIZINISCHE HOCHSCHULE HANNOVER Germany EU contribution € 110 000,00 Address Carl-neuberg-strasse 1 30625 Hannover See on map Region Niedersachsen Hannover Region Hannover Activity type Higher or Secondary Education Establishments Administrative Contact Frank Dittrich (Mr.) Links Contact the organisation Opens in new window Website Opens in new window FLEET BIOPROCESSING LIMITED United Kingdom EU contribution € 576 800,00 Address Pale lane pale lane farm unit 6 RG27 8DH Hartley wintney hants See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Adrian Wilkinson (Dr.) Links Contact the organisation Opens in new window Website Opens in new window BIOCARTIS SA Participation ended Switzerland EU contribution € 291 890,00 Address Epfl quartier de l innovation - building g 1015 Lausanne See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Patrick Van Den Bogaard (Dr.) Links Contact the organisation Opens in new window Website Opens in new window RESEARCH NETWORK SERVICES LIMITED United Kingdom EU contribution € 240 000,00 Address St john street 145-157 2nd floor EC1V 4PY London See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Erik Werner (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ Germany EU contribution € 57 876,00 Address Langenbeckstrasse 1 55131 Mainz See on map Region Rheinland-Pfalz Rheinhessen-Pfalz Mainz, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Uta Veith (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET Norway EU contribution € 84 084,00 Address Hansine hansens veg 14 9019 Tromso See on map Region Norge Nord-Norge Troms og Finnmark Activity type Higher or Secondary Education Establishments Administrative Contact Anne Fismen (Ms.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA CATTOLICA DEL SACRO CUORE Italy EU contribution € 56 212,00 Address Largo gemelli 1 20123 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Administrative Contact Filippo Leone (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAET GREIFSWALD Germany EU contribution € 67 376,00 Address Domstrasse 11 17489 Greifswald See on map Region Mecklenburg-Vorpommern Mecklenburg-Vorpommern Vorpommern-Greifswald Activity type Higher or Secondary Education Establishments Administrative Contact Andrea Völker (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY COLLEGE LONDON United Kingdom EU contribution € 81 136,00 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Administrative Contact Gerta Borg-Carbott (Ms.) Links Contact the organisation Opens in new window Website Opens in new window THE QUEEN'S UNIVERSITY OF BELFAST United Kingdom EU contribution € 55 910,00 Address University road lanyon building BT7 1NN Belfast See on map Region Northern Ireland Northern Ireland Belfast Activity type Higher or Secondary Education Establishments Administrative Contact Colleen Spence (Ms.) Links Contact the organisation Opens in new window Website Opens in new window INSTITUT PASTEUR DE LILLE FONDATION France EU contribution € 53 945,00 Address Rue du professeur calmette 1 59019 Lille See on map Region Hauts-de-France Nord-Pas de Calais Nord Activity type Research Organisations Administrative Contact Fabienne Jean (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Consorci Institut Catala de Ciències Cardiovasculars Spain EU contribution € 30 310,00 Address Av. santantoni m. claret 08025 Barcelona See on map Activity type Research Organisations Administrative Contact Joaquim Escobar (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UMEA UNIVERSITET Sweden EU contribution € 48 703,00 Address Universitetomradet 901 87 Umea See on map Region Norra Sverige Övre Norrland Västerbottens län Activity type Higher or Secondary Education Establishments Administrative Contact Lars Wikman (Mr.) Links Contact the organisation Opens in new window Website Opens in new window TARTU ULIKOOL Estonia EU contribution € 74 911,00 Address Ulikooli 18 51005 Tartu See on map Region Eesti Eesti Lõuna-Eesti Activity type Higher or Secondary Education Establishments Administrative Contact Merike Leego (Ms.) Links Contact the organisation Opens in new window Website Opens in new window REGION HOVEDSTADEN Denmark EU contribution € 63 773,00 Address Kongens vaenge 2 3400 Hillerod See on map Region Danmark Hovedstaden Nordsjælland Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Gitte Fogelberg (Ms.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA DEGLI STUDI DELL'INSUBRIA Italy EU contribution € 75 239,00 Address Via ravasi 2 21100 Varese See on map Region Nord-Ovest Lombardia Varese Activity type Higher or Secondary Education Establishments Administrative Contact Giovanni Barbieri (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY OF DUNDEE United Kingdom EU contribution € 68 523,00 Address Nethergate DD1 4HN Dundee See on map Region Scotland Eastern Scotland Angus and Dundee City Activity type Higher or Secondary Education Establishments Administrative Contact Jim Mcgregor (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITATSSPITAL BASEL Switzerland EU contribution € 39 858,00 Address Hebelstrasse 32 4031 Basel See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Thomas Gruberski (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAET ULM Germany EU contribution € 46 418,00 Address Helmholtzstrasse 16 89081 Ulm See on map Region Baden-Württemberg Tübingen Ulm, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Frank Gleixner (Mr.) Links Contact the organisation Opens in new window Website Opens in new window HAMILTON HEALTH SCIENCES CORPORATION Participation ended Canada EU contribution € 0,00 Address 1280 main street west L8S 4L8 Hamilton See on map Activity type Higher or Secondary Education Establishments Administrative Contact Beena Cracknell (Ms.) Links Contact the organisation Opens in new window THE UNIVERSITY OF SYDNEY Australia EU contribution € 51 324,00 Address Camperdown campus arundel st 71/79 2006 Sydney See on map Activity type Higher or Secondary Education Establishments Administrative Contact Kate Taylor (Ms.) Links Contact the organisation Opens in new window Website Opens in new window INSTITUTO NEUROLOGICO MEDITERRANEO NEUROMED SOCIETA PER AZIONI Italy EU contribution € 19 027,00 Address Via atinense 18 86077 Pozzilli is See on map Region Sud Molise Isernia Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Emilia Belfiore (Dr.) Links Contact the organisation Opens in new window Website Opens in new window
