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Label Free Nanoscopy Using Infra Red

Objective

Every year, Alzheimer's disease (AD) affects about 800,000 new patients in Europe and directly causes 50% of dependency of aged persons. Currently there is no test to diagnose this disease. There is a great need to improve outcomes for patients with lung cancer which causes between 15-28% of all cancer deaths in Europe.

Chemical and structural imaging with nanoresolution under ambient conditions can significantly advance our understanding of biological processes at the sub-cellular level and provide understanding of early stage AD and lung cancer, improve the efficacy of therapeutic drugs and evaluate the real impact of nanomaterials to health and safety.
In production processes the ability to image defects with nanometre resolution is critical for robust quality control of ‘industrially important’ products e.g. organic photovoltaic devices, antimicrobial textiles and functional coatings on biomedical implants.
Nanoscale imaging available today does not permit in situ sub-cellular analysis and integrated metrology. This restricts our ability to optimise nanomaterials processes. Vibrational spectroscopy based imaging tools such as Infra-Red microscopy can provide a solution. Lateral resolutions of such techniques are currently limited to the micrometre range due to diffraction-limits.

This project proposes a novel imaging tool Infra Red Nanoscope (IRN) that will break away from this diffraction limit. IRN will significantly improve the lateral resolution of IR microscopy on a table-top set up from the current state-of-the-art of 100 micron to 70 nm. It will also perform 3D imaging at a resolution of 500 nm, which is currently not possible in IR microscopy. A detailed methodology and instrumentation plan exists to implement a ready to commercialise table-top, nanoresolution, IRN. The instrument offers easy operation, flexibility and label free imaging of structure and chemistry that will stimulate new research in cancer treatments and early stage diagnostics of AD.

Call for proposal

FP7-NMP-2011-SME-5
See other projects for this call

Coordinator

UNIVERSITY OF LIMERICK
Address
National Technological Park, Plassey
- Limerick
Ireland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 345 310,20
Administrative Contact
John Mulcahy (Mr.)

Participants (10)

LASERSPEC
Belgium
EU contribution
€ 455 500
Address
Rue Trieux Scieurs 15
5020 Malonne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
David Symens (Mr.)
MULTITEL
Belgium
EU contribution
€ 494 750
Address
Rue Pierre Et Marie Curie 2
7000 Mons
Activity type
Research Organisations
Administrative Contact
Bertrand Tiberghien (Mr.)
G.N.R. SRL
Italy
EU contribution
€ 292 400
Address
Via Torino 7
28010 Agrate Conturbia No
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Pisani Luigi (Dr.)
NT-MDT SERVICE & LOGISTICS LTD
Ireland
EU contribution
€ 221 200
Address
National Technological Park
Plassey
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Denis Stoiakine (Mr.)
PLASMACHEM PRODUKTIONS- UND HANDEL GMBH
Germany
EU contribution
€ 204 520
Address
Schwarzschildstrasse 10
12489 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Alexei Antipov (Dr.)
LABORATOIRE D'EVALUTION DES MATERIELS IMPLANTABLES SA
France
EU contribution
€ 70 000,16
Address
Technopole Bordeaux-montesquieu, Allée François Magendie 2
33650 Martillac
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Marie-Françoise Harmand (Dr.)
UNIVERSITATEA POLITEHNICA DIN BUCURESTI
Romania
EU contribution
€ 446 338,04
Address
Splaiul Independentei 313 Sect 6
060042 Bucharest
Activity type
Higher or Secondary Education Establishments
Administrative Contact
George Stanciu (Prof.)
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy
EU contribution
€ 379 980
Address
Via Morego 30
16163 Genova
Activity type
Research Organisations
Administrative Contact
Sara Pittaluga (Ms.)
UNIVERSITA DEGLI STUDI DI GENOVA
Italy
EU contribution
€ 240 001,60
Address
Via Balbi 5
16126 Genova
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Cinzia Leone (Dr.)
SYNCHROTRON SOLEIL SOCIETE CIVILE
France
Address
L Orme Des Merisiers
91190 Saint Aubin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Paul Dumas (Dr.)