Objective There is growing public concern about adverse effects of traffic noise on health, as research has found that traffic noise increases the risk for cardiovascular diseases. Noise is thought to act as a stressor and disturbs sleep. Though this potentially could increase the risk for other major diseases, noise effects on other than the cardiovascular diseases are virtually unexplored.The main objective of this project is to investigate if long-term exposure to road traffic noise is detrimental to various health outcomes in susceptible groups, i.e. children and elderly. Outcomes in children include low birth weight, infections and cognitive performance, and in elderly outcomes include diabetes, cancer, cancer survival, health-related quality of life and health behaviour.The basis of this proposal is two unique Danish cohorts of, respectively, 57,053 elderly and 101,042 children (a national birth cohort). Historic and present residential addresses for all cohort members will be obtained through linkage with the nationwide Central Population Registry, and exposure to road traffic noise and air pollution will be calculated by validated models at all addresses.The health outcomes will be obtained from cohort interviews/questionnaires or found through linkage with unique, nationwide, population-based health registers, such as the Danish National Hospital Registry, the Diabetes Registry and the Cancer Registry.Data will be analysed using a number of statistical analyses depending on design and the character of the endpoint variable. All analyses will be adjusted for potential confounders such as air pollution, smoking and education.Within the EU, 30% of the population lives at locations where the 55dB WHO noise limit is exceeded. Knowledge of harmful effects of noise is, however, limited. The results of the proposed research have a high potential to influence the content and time schedule of noise action plans in the EU member states. Fields of science medical and health sciencesclinical medicineendocrinologydiabetesengineering and technologyenvironmental engineeringair pollution engineeringmedical and health sciencesclinical medicinecardiologycardiovascular diseasesmedical and health sciencesclinical medicineoncologynatural sciencesearth and related environmental sciencesenvironmental sciencespollution Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-SG-LS7 - Applied life sciences, biotechnology and bioengineering: agricultural, animal, fishery, forestry/food sciences; biotechnology, chemical biology, genetic engineering, synthetic biology, industrial biosciences; environmental biotechnology. Call for proposal ERC-2011-StG_20101109 See other projects for this call Funding Scheme ERC-SG - ERC Starting Grant Coordinator KRAEFTENS BEKAEMPELSE Address Strandboulevarden 49 2100 Koebenhavn Denmark See on map Activity type Research Organisations projects.principal_investigator Mette Sørensen (Dr.) projects.administrative_contact Claus Skytte Rasmussen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 1 296 421,00 Beneficiaries (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all KRAEFTENS BEKAEMPELSE Denmark EU contribution € 1 296 421,00 Address Strandboulevarden 49 2100 Koebenhavn See on map Activity type Research Organisations projects.principal_investigator Mette Sørensen (Dr.) projects.administrative_contact Claus Skytte Rasmussen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window AARHUS UNIVERSITET Denmark EU contribution € 38 469,00 Address Nordre ringgade 1 8000 Aarhus c See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Susanne Jensen (Ms.) Links Contact the organisation Opens in new window Website Opens in new window