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HIgh Speed PRoteomics Analysis (Prot-HiSPRA): Solving the bottlenecks of proteomics technologies for time sensitive proteome driven medical decisions

Objective

The main objective of the proposed collaborative project Prot-HiSPRA is to remove time-consuming bottlenecks of existing proteomics technologies (sample preparation, fractionation, proteolysis, separation, data collection, and data mining) and bring the proteome driven analysis into time sensitive clinical practice. Prot-HiSPRA is an objective-driven research project and it aims at generating new knowledge and new technologies which will improve the European competitiveness in the field of applied proteomics. Prot-HiSPRA is planned for the duration of 36 months which is necessary in order to ensure a high-quality validation of the developed high-throughput methodologies. A strong participation of SMEs (partner 2 – MAYLAB, partner 3 – CELS - left the onsortium, partner 6 – RTDs, partner 7 - BIA) will ensure strong innovation and exploitation during HiSPRA. Research activities in the Prot-HiSPRA program can be divided into a technological core project that is tailored to significantly improve on technologies in the fields of proteomics, bioinformatics, and integrated biology. Analytical methods developed with the Prot-HiSPRA project will be exemplified by applying for analysis of clinical samples originating from in vitro fertilization (IVF) procedures. During the IVF process, especially at the moment when decisions are made which embryo can be implanted, decisions must be made so that the process has the greatest chance for success. To further elevate pregnancy rates for IVF a non-invasive, rapid, and robust methods for judging the embryos status is urgently needed to examine the embryos´ proteome. These methods could not only be applied in the described field of reproductive medicine but also in any the other fields of clinical analysis where fast and reliable diagnosis on a proteomic basis could be made available.

Call for proposal

FP7-HEALTH-2011-single-stage
See other projects for this call

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Address
Spitalgasse 23
1090 Wien
Austria
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 325 422,65
Administrative Contact
Rainer Schmid (Prof.)

Participants (6)

MAYLAB ANALYTICAL INSTRUMENTS GMBH
Austria
EU contribution
€ 380 960
Address
Postgasse 11
1010 Vienna
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Hans Mayrhofer (Mr.)
CENTRE OF EXCELLENCE FOR LIFE SCIENCES LTD

Participation ended

United Kingdom
EU contribution
€ 4 392,34
Address
Quorum 16
NE12 8BX Newcastle Upon Tyne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Catharine Little (Ms.)
DEBRECENI EGYETEM
Hungary
EU contribution
€ 214 200
Address
Egyetem Ter 1
4032 Debrecen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Zoltán Pozsonyi (Mr.)
THE RUSSIAN ACADEMY OF SCIENCES INSTITUTION INSTITUTE FOR ENERGY PROBLEMS OF CHEMICAL PHYSICS OF RAS
Russia
EU contribution
€ 247 712
Address
Leninsky Prospekt 38 Bld 2
119334 Moskva
Activity type
Research Organisations
Administrative Contact
Tatiana Nikitina (Ms.)
MOSER ANDREAS MAS
Austria
EU contribution
€ 154 080
Address
Sylvester Jordan Strasse 13 Top 4
6094 Axams
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Andreas Moser (Mr.)
BIA SEPARATIONS DOO
Slovenia
EU contribution
€ 209 480
Address
Mirce 21
5270 Ajdovscina
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jana Kuzmanic (Ms.)