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Transnational access and enhancement of integrated Biological Structure determination at synchrotron X-ray radiation facilities

Objective

The BioStruct-X consortium has 19 partners from 11 EU member and associated states, who lead in facility provision and research in structural biology using high brilliance X-rays, provided by state-of-the art synchrotrons and a free electron laser. BioStruct-X will provide integrated transnational access via 42 installations in four key areas: macromolecular X-ray crystallography, small angle X-ray scattering, X-ray imaging, protein production and high-throughput crystallisation. All installations provide on-line data analysis tools and remote experiment control. Transnational access will be critically enhanced by four targeted joint research activities: a) new data processing tools, to the benefit of access to applications in macromolecular X-ray crystallography; b) an integrated on-line sample characterisation system, to the benefit of the access to small angle X-ray scattering, c) correlated fluorescence light microscopy components that will enhance X-ray imaging applications offered for access; d) a toolbox for mammalian cell line expression, to the direct benefit of the access to protein production facilities. The BioStruct-X project will offer a central Batch Allocation Group proposal mechanism to promote project excellence by combining different methods and encouraging multi-site applications. The networking activity integrates all activities and combines them with those of other I3 actions under the ESFRI project INSTRUCT for future coordinated infrastructure activities in structural biology. The efficient management structure has four transparent layers: the coordinator, a six-member executive board, three work package coordinators and the general assembly comprising three user representatives and all partners. Thus, BioStruct-X will establish a state-of-the-art coordinated and multi-site infrastructure for current and emerging key methods in 21st century structural biology, thus advancing the European Research Area in biomedical sciences.

Field of science

  • /natural sciences/computer and information sciences/data science/data analysis
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins
  • /natural sciences/computer and information sciences/data science/data processing
  • /natural sciences/biological sciences/molecular biology/structural biology
  • /natural sciences/earth and related environmental sciences/geology/mineralogy/crystallography

Call for proposal

FP7-INFRASTRUCTURES-2011-1
See other projects for this call

Funding Scheme

CP-CSA-Infra - Combination of CP and CSA

Coordinator

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Address
Meyerhofstrasse 1
69117 Heidelberg
Germany
Activity type
Research Organisations
EU contribution
€ 2 769 109,80
Administrative Contact
Phil Irving (Dr.)

Participants (18)

CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON
Spain
EU contribution
€ 152 606,10
Address
Carrer De La Llum 2-26
08290 Cerdanyola Del Valles Barcelona
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Alejandro Sanchez Grueso (Dr.)
STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY
Germany
EU contribution
€ 181 706,44
Address
Notkestrasse 85
22607 Hamburg
Activity type
Research Organisations
Administrative Contact
Ute Krell (Dr.)
DIAMOND LIGHT SOURCE LIMITED
United Kingdom
EU contribution
€ 1 531 018,34
Address
Diamond House Harwell Science & Innovation Campus Chilton
0X11 0DE Didcot
Activity type
Other
Administrative Contact
Dominic Peter Semple (Dr.)
ELETTRA - SINCROTRONE TRIESTE SCPA
Italy
EU contribution
€ 129 217,31
Address
Ss 14 Km 163.5 Area Science Park
34149 Basovizza Trieste
Activity type
Research Organisations
Administrative Contact
Giorgio Paolucci (Dr.)
HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH
Germany
EU contribution
€ 1 067 312,60
Address
Hahn Meitner Platz 1
14109 Berlin
Activity type
Research Organisations
Administrative Contact
Thomas Van Issem (Mr.)
MAX IV Laboratory, Lund University
Sweden
EU contribution
€ 406 057,08
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marjolein Thunnissen (Dr.)
PAUL SCHERRER INSTITUT
Switzerland
EU contribution
€ 973 117,04
Address
Forschungstrasse 111
5232 Villigen Psi
Activity type
Research Organisations
Administrative Contact
Stefan Müller (Mr.)
SYNCHROTRON SOLEIL SOCIETE CIVILE
France
EU contribution
€ 630 015,90
Address
L Orme Des Merisiers
91190 Saint Aubin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Yves Le Ray (Mr.)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 404 900,72
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Stephen Conway (Dr.)
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 150 619,50
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
Eusebio Jiménez Arroyo (Mr.)
DECTRIS AG
Switzerland
EU contribution
€ 34 964,10
Address
Taefernweg 1
5405 Dattwil Ag
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Clemens Schulze-Briese (Dr.)
EUROPEAN SYNCHROTRON RADIATION FACILITY
France
EU contribution
€ 226 479,94
Address
71 Avenue Des Martyrs
38000 Grenoble
Activity type
Research Organisations
Administrative Contact
Ian Lishman (Mr.)
EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH
Germany
EU contribution
€ 99 555
Address
Holzkoppel 4
22869 Schenefeld
Activity type
Other
Administrative Contact
Chiara Bearzotti (Ms.)
OULUN YLIOPISTO
Finland
EU contribution
€ 49 814,92
Address
Pentti Kaiteran Katu 1
90014 Oulu
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Arto Eljander (Mr.)
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
Portugal
EU contribution
€ 49 814,92
Address
Avenida Da Republica, Estacao Agronomica Nacional
2784-505 Oeiras
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maria Arménia Carrondo (Prof.)
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 49 814,92
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Talia Tzahor (Ms.)
TERMESZETTUDOMANYI KUTATOKOZPONT
Hungary
EU contribution
€ 49 814,92
Address
Magyar Tudosok Korutja 2
1117 Budapest
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Beata Vertessy (Dr.)
MALVERN PANALYTICAL LIMITED
United Kingdom
EU contribution
€ 43 694,50
Address
Grovewood Road Enigma Business Park
WR14 1XZ Malvern
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Mark Wingfield (Dr.)