Objective
The BioStruct-X consortium has 19 partners from 11 EU member and associated states, who lead in facility provision and research in structural biology using high brilliance X-rays, provided by state-of-the art synchrotrons and a free electron laser. BioStruct-X will provide integrated transnational access via 42 installations in four key areas: macromolecular X-ray crystallography, small angle X-ray scattering, X-ray imaging, protein production and high-throughput crystallisation. All installations provide on-line data analysis tools and remote experiment control. Transnational access will be critically enhanced by four targeted joint research activities: a) new data processing tools, to the benefit of access to applications in macromolecular X-ray crystallography; b) an integrated on-line sample characterisation system, to the benefit of the access to small angle X-ray scattering, c) correlated fluorescence light microscopy components that will enhance X-ray imaging applications offered for access; d) a toolbox for mammalian cell line expression, to the direct benefit of the access to protein production facilities. The BioStruct-X project will offer a central Batch Allocation Group proposal mechanism to promote project excellence by combining different methods and encouraging multi-site applications. The networking activity integrates all activities and combines them with those of other I3 actions under the ESFRI project INSTRUCT for future coordinated infrastructure activities in structural biology. The efficient management structure has four transparent layers: the coordinator, a six-member executive board, three work package coordinators and the general assembly comprising three user representatives and all partners. Thus, BioStruct-X will establish a state-of-the-art coordinated and multi-site infrastructure for current and emerging key methods in 21st century structural biology, thus advancing the European Research Area in biomedical sciences.
Field of science
- /natural sciences/computer and information sciences/data science/data analysis
- /natural sciences/biological sciences/biochemistry/biomolecules/proteins
- /natural sciences/computer and information sciences/data science/data processing
- /natural sciences/biological sciences/molecular biology/structural biology
- /natural sciences/earth and related environmental sciences/geology/mineralogy/crystallography
Call for proposal
FP7-INFRASTRUCTURES-2011-1
See other projects for this call
Funding Scheme
CP-CSA-Infra - Combination of CP and CSACoordinator
69117 Heidelberg
Germany
Participants (18)
08290 Cerdanyola Del Valles Barcelona
22607 Hamburg
0X11 0DE Didcot
34149 Basovizza Trieste
14109 Berlin
22100 Lund
5232 Villigen Psi
91190 Saint Aubin
OX1 2JD Oxford
28006 Madrid
5405 Dattwil Ag
38000 Grenoble
22869 Schenefeld
90014 Oulu
2784-505 Oeiras
7610001 Rehovot
1117 Budapest
WR14 1XZ Malvern