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Content archived on 2024-05-29

Microfluidic microdroplet femtoreactors

Objective

.We aim to develop a technology based on compartmentalising billions of experiments into separate microdroplets in microfluidic devices. These microdroplets, which can have a volume as small as ~5 femtolitres, are separated from other microdroplets by an immiscible phase. Identical microdroplets (<3% polydispersity) can be formed rapidly (at up to 104s-1), allowing ultra-high throughput (109 per day).

Furthermore, the microdroplets can be fused, allowing reagents to be mixed in a combinatorial manner, and reactions to be started, stopped or modified at defined times. Splitting microdroplets allows their contents to be aliquoted. If the reactions result in an optical signal, a spatially-resolved optical image of the microfluidic network will allow reaction kinetics to be determined. It will also be possible to separate microdroplets using a microfluidic flow sorter to allow recovery and further analysis or manipulation of the molecules they contain, notably by mass spectrometry.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2004-NEST-C-1
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (3)

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