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Content archived on 2024-05-29

Advanced near field optical tools with biochemical functional recognition at the single molecular level

Objective

In this proposal we aim at developing truly novel optical scanning probe tools to allow nanometric local probing, interrogation, manipulation and dissection of biological function at the level of single molecules in their native environment: the living cell. Our objectives are two-fold: First, to pioneer the development of a novel multi-parameter scanning probe microscope able to provide for the first time simultaneous topographic, optical and biochemical recognition in one and the same instrument. Second, we will exploit the newly devised technology to unravel the organisation and dynamics of the cell surface receptor landscape at the nanometre scale in relation to cell function.

As such, the proposal is fully compatible with the NEST-ADVENTURE objectives since the research is focussed on the development of an entirely new technology which, if successful, will not only open up new avenues for progress in fundamental and applied sciences but also for biotech- and high tech instrumentation- industry. Furthermore, it has a high risk character since we will attempt to enter into an uncharted territory combining areas of nano-instrumentation, nano-photonics and nanometre scale biology. In order to maximise the chances of success we have chosen for an interdisciplinary, trans-national and multi-institutional (research institutions, high education centres and industry) partnership. Thus, our working strategy will rely on the strong cooperation between the different partners, which as added value will also lead to a strengthening of cohesion in European research. In the long term we expect that both, fundamental researchers (material science, surface chemistry) as well as industrial sectors (nano-technology enterprises and the biotechnology and pharmaceutical industries) will benefit from this new technology.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2004-NEST-C-1
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

FUNDACIÓ PRIVADA INSTITUT DE BIOENGINYERIA DE CATALUNYA
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (4)

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