Objectif
RNA molecules are at the heart of life. It is now commonly admitted that nearly all the human genome is transcribed, and a wealth of new coding and non-coding RNAs have been discovered. Importantly, modern RNAs are never naked, but always exist in complex with proteins to form RNPs (Ribonucleoproteins). In the case of non-coding RNAs, these proteins are usually stably associated with the RNA and help to perform their function. In contrast, RNA binding proteins are usually transiently bound to coding RNAs, and control various aspects of their metabolism. For the next generation of scientists, a great challenge will be to understand the function and the mechanisms of action of the myriads of RNPs.
The goal of this ITN (“RNPnet”) is first to bring together existing labs from different discipline, to join forces and tackle key questions in the field, and second, to produce highly-trained young researchers that will be sensitized to RNA and possess a multidisciplinary approach to research. The multiple expertises present in the fifteen labs of this network will be used in a highly cooperative and integrated manner. The research training will focus on studying RNPs involved in mRNA surveillance, splicing and editing. In addition, a total of fifteen meetings including two summer schools and several workshops are planed to strengthen education and interaction among participants of RNPnet.
Finally, another important aspect of RNPnet is the presence of two industrial partners. Their aim is to use the enormous potential of RNA biology in therapeutic applications, either by modifying RNAs and using it as a drug, or by targeting specific RNA binding proteins with small molecules. We foresee that the presence of industrial partners will be highly beneficial for the students, and that, by exposing them to both the academic and industrial world, we will both facilitate communication between these worlds and provide to the young trainees a large panorama of their possible career.
Champ scientifique
Appel à propositions
FP7-PEOPLE-2011-ITN
Voir d’autres projets de cet appel
Régime de financement
MC-ITN - Networks for Initial Training (ITN)Coordinateur
8092 Zuerich
Suisse
Voir sur la carte
Participants (14)
69117 Heidelberg
Voir sur la carte
75794 Paris
Voir sur la carte
75230 Paris
Voir sur la carte
1649 028 Lisboa
Voir sur la carte
80539 Munchen
Voir sur la carte
08002 Barcelona
Voir sur la carte
4056 Basel
Voir sur la carte
6020 Innsbruck
Voir sur la carte
370 05 Ceske Budejovice
Voir sur la carte
W1B 1AL LONDON
Voir sur la carte
4051 Basel
Voir sur la carte
Participation terminée
34293 Montpellier
Voir sur la carte
75008 PARIS
Voir sur la carte
Participation terminée
10117 Berlin
Voir sur la carte