Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS
Content archived on 2024-06-16

Viral vector and RNAi strategies to determine the role of beta2 containing nicotinic receptors in aversive learning

Objective

Dr. Sarah King has recently returned (August 2004) to the UK after working for seven years in the Department of Psychiatry, Yale University, USA. As a new Lecturer in the Department of Psychology at the University of Sussex (permanent position) Dr. King endeavours to set up an active and internationally competitive research programme studying the actions of nicotine and role of nicotinic receptors (nAChRs) in brain function and psychiatric disorders. Dr. King requests funds to aid this reintegration back in to Sussex, the UK and Europe by supporting the costs of a technician, equipment and consumables. In the USA, Dr. King worked with transgenic mice, generating lines with temporal and region specific expression of beta2 subunit containing nAChRs, and tested hypotheses as to the brain circuitry underlying the role of nAChRs in behavioural processes. By bringing the expertise and knowledge gained in the USA back to the UK, Dr. King wants to further develop and use new genetic tools to study nAChR function in vivo.

Combining the transgenic work with cutting edge techniques, viral-mediated gene transfer and RNA interference, will provide novel and efficient methods to study nAChR function. These tools will be used to determine the brain circuits in which nicotine acts to enhance aversive learning. This work falls into the objectives of the 6th Framework Programme. Dr. King is an ideal candidate for a Marie Curie Mobility Action International Reintegration Grant. Having returned to the UK from the USA, she can introduce these new and cutting edge techniques, and provide an invaluable contribution to the European research community, by advancing European research in the field through her essential knowledge, experience and position. Dr. King's research objectives and plan fit solidly into the Life Sciences, genomics and biotechnology for health research area, specifically on the research topic's studying the brain and combating diseases of the nervous system.

Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2004-MOBILITY-12
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

IRG - Marie Curie actions-International re-integration grants

Coordinator

UNIVERSITY OF SUSSEX
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data
My booklet 0 0