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Content archived on 2024-05-28

Development of a three-dimensional Reconstruction Algorithm for Phase Contrast Breast Tomosynthesis

Objective

Breast cancer remains the most common cause of death for women below seventy years of age. In Europe, one in ten women will develop breast cancer in her lifetime. Early diagnosis is recognised as a critical factor that can improve the chance of survival. X-ray mammography is currently considered best practice for screening and early diagnosis of breast carcinoma. However, a significant number of breast cancers remain undetected when using conventional 2D mammography imaging, due to insufficient soft tissue contrast and the effect of overlying anatomical structures.

A method that combines the advantages of the phase contrast imaging and digital breast tomosynthesis may result in high contrast tomograms with well outlined breast cancer margins.

This project will aim to develop, test and validate a three-dimensional reconstruction algorithm for phase contrast digital breast tomosynthesis. The overall objective will be pursued through the following specific objectives that will be addressed in a number of highly innovative tasks of design, modelling, numerical simulations and experimental work: (a) Development of a simulation tool for generation of phase contrast images over limited angular range; (b) Development of a three-dimensional algorithm for phase contrast breast tomosynthesis; (c) Validation and further refinement of the algorithm with computer models of ground truth phantoms as well with physical phantoms that will be exploited at laboratory environment.

The availability of three-dimensional reconstruction algorithms dedicated for phase contrast breast tomosynthesis will provide a possibility to study the potential of this novel technique to enhance contours of different breast soft tissues, thus resulting in clearly visible three dimensional soft tissue morphology.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2011-CIG
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-CIG - Support for training and career development of researcher (CIG)

Coordinator

TECHNICAL UNIVERSITY OF VARNA
EU contribution
€ 100 000,00
Address
UL STUDENTSKA 1
9010 Varna
Bulgaria

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Region
Северна и Югоизточна България Североизточен Варна
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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