Objective
Sigmoid Biotechnologies, an Irish Drug Delivery Systems Development SME established in 2003, has developed a novel oral controlled release technology, Liquid and Emulsion Drug Delivery System or LEDDS. LEDDS enables the controlled release of difficult to formulate drugs that are optimally formulated in various liquid or emulsion formats. To date, Sigmoid has demonstrated that LEDDS is effective in delivering small molecule as well as cyclic peptide drugs.
Going forward, Sigmoid has recognised that a modified LEDDS format would have significant potential to orally delivery biopharmaceutical drugs such as peptides and proteins. The LEDDS modification will require that Sigmoid strengthens its knowledge of lipid and emulsion formulation technologies, bioadhesive polymer synthesis and development as well as establishing an in-house intelligent in vitro drug formulation screening technology. To facilitate this development, a multidisciplinary work programme has been planned and will involve Sigmoid collaborating with and transferring personnel amongst four EU laboratories based in Poland, Italy, Germany and Ireland, each recognised as world class in their respective fields.
Developing an integrated LEDDS-enabled oral biopharmaceutical delivery system will lead to the development of significant patent protection and increase Sigmoid's competitive position in the drug delivery industry in general and in the area of biopharmaceutical delivery in particular. Sigmoid's partners will benefit from acquiring knowledge of LEDDS technology as well as industrial training in a cGMP facility. Also, visiting scientists will have opportunities to publish and present the work carried out as well as being encouraged to file patents.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences chemical sciences polymer sciences
- natural sciences biological sciences biochemistry biomolecules lipids
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-3
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
DUBLIN
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.