Objective
My long term goal is to establish a network of bacterial factors and the host signalling pathways they modulate in wild type and mutated intestinal cells that predispose for inflammation and cancer. The work of my future team will ultimately lead to a deeper understanding of critical aspects of intestinal human disease, including inflammatory bowel disease and the intestinal tumor formation and metastasis. To rapidly assess numerous combinations of inflammatory and anti-inflammatory host genes, bacterial species and their excreted factors we will use in this proposal Drosophila genetics and transcriptome analysis, chemical treatments and microbiological assays to identify the host and microbial factors that mediate inflammation and predispose for cancer using Drosophila. Despite the physiological divergence that exists between vertebrates and insects, modelling of human diseases is possible because of the high degree of conservation between Drosophila and mammalian signalling pathways controlling inflammation and infection.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- medical and health sciences clinical medicine gastroenterology inflammatory bowel disease
- medical and health sciences clinical medicine oncology
- natural sciences biological sciences zoology entomology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-CIG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
1678 Nicosia
Cyprus
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.