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High-resolution image-based computational inner ear modelling for surgical planning of cochlear implantation

Objective

Cochlear implantation is a surgical procedure that aims to overcome hearing loss by direct electrical stimulation of the spiral ganglion cells in the cochlea of the inner ear. The surgical scenario of implantation surgery is very complex. It requires high clinical expertise in order to 1) efficiently access the surgical site, the cochlea, localize nearby critical structures (e.g. facial nerve) and 2) optimize the position of the implantable device (electrode array) inside the cochlea. Furthermore, there is a vast anatomical variability amongst patients. This makes individual optimal fitting an extremely difficult task and strongly influences the success of the surgery and subsequently hearing restoration.
We hypothesize that a comprehensive understanding of the shape variability of the middle and inner ear among patients will enable the design improvement of hearing implants, and will be of assistance during surgical planning. Consequently, the aim of this project is: 1) to develop a novel high-resolution high-energy microCT device to obtain detailed images of the middle and inner ear, even in the presence of metallic implants, 2) to build a model of the shape variability of the middle and inner ear from high-resolution images, also incorporating functional information, 3) to build a computer-assisted patient-specific preoperative planning system, and 4) to improve the design of cochlear implant (CI) electrode arrays and associated insertion tools using a population-based optimization framework. All objectives revolve around the criteria of minimizing invasiveness, insertion-induced trauma and enhanced functional outcome through patient-specific frequency mapping.
The consortium is composed of two research-intensive SMEs, one university hospital, two universities, and a large European enterprise. This project will lead to important strategic benefits for all partners, and very especially for the SMEs.

Field of science

  • /medical and health sciences/clinical medicine/surgery/surgical procedure
  • /medical and health sciences/medical biotechnology/implants

Call for proposal

FP7-HEALTH-2012-INNOVATION-2
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

UNIVERSIDAD POMPEU FABRA
Address
Placa De La Merce, 10-12
08002 Barcelona
Spain
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 202 800
Administrative Contact
Eva Martin (Mrs.)

Participants (5)

UNIVERSITAET BERN
Switzerland
EU contribution
€ 671 740
Address
Hochschulstrasse 6
3012 Bern
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mauricio Reyes Aguirre (Dr.)
MED-EL Elektromedizinische Geraete GmbH
Austria
EU contribution
€ 262 965
Address
Fuerstenweg 77A
6020 Innsbruck
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Raimund Naschberger (Mr.)
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 568 579,75
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mikkel Boel (Mr.)
SCANCO MEDICAL AG
Switzerland
EU contribution
€ 984 400
Address
Fabrikweg 2
8306 Bruettisellen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Bruno Koller (Dr.)
Alma IT Systems, S.L.
Spain
EU contribution
€ 860 800
Address
Vilana 4B 4-1
08022 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Miguel ángel González Ballester (Dr.)