Objectif High-throughput sequencing (HTS) is a powerful and rapidly evolving family of technologies with a multitude of applications. They include genetics of rare and common diseases, understanding of disease mechanism and progression through transcriptome and epigenome profiling, cancer stratification, personalised medicine and molecular systems biology of gene regulation. The genome, epigenome, transcriptome and interactome are all intricately connected, and modern HTS technology can probe all of these -omic levels. Statistical analysis is a crucial component of many experiments and studies, and the quality and efficiency of the analysis often determines the success of a project.In this collaborative project we will develop a range of new statistical analysis tools to solve open problems in HTS data analysis, ranging from low-level processing of sequence reads up to systems-level modelling of disease associated and cellular processes. We will provide to a wide audience an integrated computational framework for HTS data analysis and interpretation that is robust, efficient and user-friendly. We will establish improved procedures for the publishing of statistical software as an integral part of the scientific publication process, within the framework of the Bioconductor project. We will provide tools to benchmark experimental protocols and statistical methods, and we will provide training materials and a extensive training programme to rapidly disseminate these new tools to the broader biomedical community.SME partners will integrate these new tools within their analysis pipelines with associated user-friendly commercial software providing access to their additional proprietary tools. SMEs will benefit from basic methodology development done in a public, pre-competitive arena and will be able to use these technologies to enhance their products and services. Champ scientifique natural sciencescomputer and information sciencesdata sciencenatural sciencescomputer and information sciencessoftwaremedical and health sciencesclinical medicineoncologymedical and health scienceshealth sciencespersonalized medicinenatural sciencesbiological sciencesgeneticsgenomes Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Thème(s) HEALTH.2012.2.1.1-3 - Statistical methods for collection and analysis of -omics data Appel à propositions FP7-HEALTH-2012-INNOVATION-1 Voir d’autres projets de cet appel Régime de financement CP-FP - Small or medium-scale focused research project Coordinateur THE UNIVERSITY OF MANCHESTER Contribution de l’UE € 635 452,00 Adresse OXFORD ROAD M13 9PL Manchester Royaume-Uni Voir sur la carte Région North West (England) Greater Manchester Manchester Type d’activité Higher or Secondary Education Establishments Contact administratif Katherine Boylan (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Participants (9) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire Genomatix Software GmbH Allemagne Contribution de l’UE € 439 000,00 Adresse Bayerstrasse 85a 80335 Muenchen Voir sur la carte Région Bayern Oberbayern München, Kreisfreie Stadt Contact administratif Korbinian Grote (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée GENOMNIA SRL Italie Contribution de l’UE € 306 059,60 Adresse CORSO MAGENTA 56 20123 MILANO Voir sur la carte Région Nord-Ovest Lombardia Milano Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Cinzia Ferraro (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée EUROPEAN MOLECULAR BIOLOGY LABORATORY Allemagne Contribution de l’UE € 531 472,20 Adresse Meyerhofstrasse 1 69117 Heidelberg Voir sur la carte Région Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Type d’activité Research Organisations Contact administratif Virginia Otón García (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée FONDAZIONE TELETHON ETS Italie Contribution de l’UE € 187 500,00 Adresse VIA VARESE 16/B 00185 Roma Voir sur la carte Région Centro (IT) Lazio Roma Type d’activité Research Organisations Contact administratif Irene Mearelli (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA Italie Contribution de l’UE € 256 862,40 Adresse VIA MOREGO 30 16163 Genova Voir sur la carte Région Nord-Ovest Liguria Genova Type d’activité Research Organisations Contact administratif Alessandra Gastaldi (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS France Contribution de l’UE € 315 428,00 Adresse BOULEVARD SAINT MICHEL 60 75272 Paris Voir sur la carte Région Ile-de-France Ile-de-France Paris Type d’activité Research Organisations Contact administratif Florence Thépenier (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée University of Zurich Suisse Contribution de l’UE € 356 758,00 Adresse RAMISTRASSE 71 8006 ZURICH Voir sur la carte Type d’activité Higher or Secondary Education Establishments Contact administratif Mark Robinson (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Royaume-Uni Contribution de l’UE € 268 776,00 Adresse TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge Voir sur la carte Région East of England East Anglia Cambridgeshire CC Type d’activité Higher or Secondary Education Establishments Contact administratif Renata Shaeffer (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée THE UNIVERSITY OF SHEFFIELD Royaume-Uni Contribution de l’UE € 374 941,20 Adresse FIRTH COURT WESTERN BANK S10 2TN Sheffield Voir sur la carte Région Yorkshire and the Humber South Yorkshire Sheffield Type d’activité Higher or Secondary Education Establishments Contact administratif Joanne Watson (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
