Objective
The success of Evo-devo has boosted the interest in the relationship between genotypes and phenotypes. This in turn makes biologists aware of the importance of the environmental effects for genetic and evolutionary studies. The developmental processes involved in the control of environmental sensitivity, namely, phenotypic plasticity and its counterpart, canalisation, have therefore attracted much attention from evolutionary biologists in the past decade.
Plasticity is the ability of an organism to produce a different phenotype in different environments whereas canalisation refers to the ability to remain phenotypically constant in spite of varying conditions. Remarkably, the genetic and developmental bases of phenotypic plasticity and canalisation remain in most cases obscure. Instead of the classic strategy consisting in looking for QTLs and inferring potential corresponding genes, I suggest a different approach. I propose to investigate the genetic basis of plasticity and canalisation in a model whose development is known in great detail, the Drosophila wing, allowing us to test directly for the implication of known genes in environmental sensitivity. I will develop an approach combining the use of candidate genes and the powerful and flexible tools of geometric morphometrics, with a design involving environmental manipulation of wild-derived inbred lines.
I suggest this will allow:
(1) to understand the genetic bases of phenotypic plasticity and canalisation and their variation in the wild;
(2) to characterize the relationships between these two developmental processes
(3) to precise the status of the buffering of developmental noise (measured by fluctuating symmetry (FA)) in regard of plasticity and canalisation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
You need to log in or register to use this function
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.