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Content archived on 2024-06-18

Chemotherapy guidance based on efficacy of treatment regimen in cancer cells from the individual patient

Objective

The ChemoGuide project will clinically validate a proto-type technology (2treat) developed in the previous “Research for SMEs” project, “Integrated Chemical Synthesis and Cell screening in patient cells (ICSC). The project will execute a clinical study to evaluate the 2treat test’s capability of predicting which combination therapy that is most efficacious and show no resistance in the individual colorectal cancer patient. The prediction is based on reading the cell functional output cancer cells isolated from the individual patient. The clinical study will serve to verify the capability and robustness of the 2treat test. The 2treat test is formatted as an easy-to-use, disposable test array.
Colorectal cancer is now the most diagnosed cancer in EU, and the prognosis of especially stage III and IV patients is very poor. The 2treat test is expected to provide a major benefit to these patients by significantly improving the Prognosis Free Survival (PFS). Importantly oncologist will be provided the first technology that is capable of testing the cell-functional output of all combination treatment regimens used for treatment of colorectal cancer in Europe and USA before a first line treatment is launched. The technology will both improve treatment quality for the individual patient and raise the cost efficiency providing a positive impact on the health care systems.

Call for proposal

FP7-SME-2012
See other projects for this call

Coordinator

2CUREX A/S
EU contribution
€ 426 160,00
Address
FRUEBJERGVEJ 3
2100 Kobenhavn
Denmark

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Region
Danmark Hovedstaden Byen København
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ole Thastrup (Dr.)
Links
Total cost
No data

Participants (4)