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Initial Training Network for Neurogical disorders orchestrated by cytoKines

Objective

Neuroinflammatory disease, in particular multiple sclerosis affects more than 700.000 people within Europe alone. European countries are at the forefront of neuroimmunological research and students in medicine and biology are greatly attracted by the field. Neuroimmunology research further impacts our understanding of the ethiopathology of other CNS-disorders including Alzheimer’s Dementia and Morbus Parkinson. The ability of inflammatory immune cells to cause tissue damage within the nervous system is largely governed by soluble mediators including cytokines/chemokines, cytolytic molecules and growth factors. The therapeutic targeting of such mediators has proven successful for the treatment of a number of inflammatory diseases, yet is failing for the treatment of neuroinflammatory disorders. Clearly, the rules and regulatory elements, which govern inflammation and tissue injury within the CNS, differ significantly from those of other tissues and a unique CNS-focused research approach to unravel these rules is required.
In this ITN proposal, we will train ESRs and ERs specifically in Neuroimmunology by combining prominent laboratories in academia and industry on the task to study the communication networks between immune and CNS-resident cells.
Scientifically, we focus particularly on the soluble factors mediating cell-cell communication at the immune-CNS interface. To this end, we combine expertise in molecular and cellular Neuroimmunology with Neuropathology of human and animal models of CNS inflammation. In addition, our goal is to further utilize inflammatory processes for neuroprotection.

Call for proposal

FP7-PEOPLE-2012-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ
Address
Langenbeckstrasse 1
55131 Mainz
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 666 616,50
Administrative Contact
Silvia Tschauder (Dr.)

Participants (12)

University of Zurich
Switzerland
EU contribution
€ 551 009,80
Address
Ramistrasse 71
8006 Zurich
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Burkhard Becher (Prof.)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 469 709,40
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Administrative Contact
Muriel Bouas (Ms.)
MEDIZINISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 244 051,72
Address
Spitalgasse 23
1090 Wien
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Hans Lassmann (Prof.)
UNIVERSITA VITA-SALUTE SAN RAFFAELE
Italy
EU contribution
€ 244 687,96
Address
Via Olgettina 58
20132 Milano
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maria Rosa Pedrazzi (Dr.)
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 228 463,84
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Talia Tzahor (Ms.)
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Participation ended

Netherlands
EU contribution
€ 115 103,11
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jon Laman (Prof.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 225 918,88
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Anja Stielow (Ms.)
MILTENYI BIOTEC GMBH
Germany
EU contribution
€ 146 950,54
Address
Friedrich Ebert Strasse 68
51429 Bergish Gladbach
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Sabrina Schmitz (Mrs.)
APITOPE TECHNOLOGY (BRISTOL) LTD
United Kingdom
EU contribution
€ 288 906,64
Address
Bristol & Bath Science Park, Dirac Cresent, Emersons Green
BS16 7FR Bristol
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Keith Martin (Dr.)
PHENEX PHARMACEUTICALS AG
Germany
EU contribution
€ 114 884,44
Address
Donnersbergweg 1
67059 Ludwigshafen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Hoffmann (Mr.)
BIONTECH AG
Germany
EU contribution
€ 114 884,44
Address
Holderlinstrasse 8
55131 Mainz
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
John Castle (Dr.)
ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands
Address
Hanzeplein 1
9713 GZ Groningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Klaas Martens (Mr.)