Objective
HEVAR is a collaborative project involving four academic laboratories from four European countries (France, Switzerland, Germany, Italy) and four academic laboratories belonging to three South American countries (Argentine, Brazil, Uruguay). The overall scientific goal of HEVAR is to contribute to a better understanding of the immune biology of rotavirus infections using a novel generation of gene transfer vectors derived from herpes virus simplex type 1 (HSV-1), as a first step towards the development of innovative genetic vaccines to fight against these pathogens, which are the most common cause of severe dehydrating diarrhoea in young children of developing countries. In addition to contributing to a better understanding of the immune biology of rotavirus infection and of evaluating the feasibility of using HSV-1 vectors as anti-rotavirus vaccines, the main deliverables of HEVAR will be a set of toolboxes containing a large collection of HSV-1-based and DNA-based vectors expressing human and mouse rotavirus antigens that will be evaluated in mice, which will be rendered accessible to any academic team wishing to use them for vaccine development or fundamental research on rotaviruses.
A last set of deliverables will consist in a series of scientific meetings and events required to achieve the transfer of knowledge and complex technology required to generate, produce, and evaluate, the HSV-1-based gene transfer vectors in South America, therefore improving the human capital and the technological competence of these countries. In addition, the transfer from South American partners to European teams of up-to-date knowledge on the biology of rotavirus and other endemic viruses, with high social cost in South America, will strength the awareness to-, and a better understanding of-, these neglected diseases.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology genetic engineering gene therapy
- medical and health sciences basic medicine immunology immunisation
- natural sciences biological sciences microbiology virology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- medical and health sciences health sciences infectious diseases DNA viruses
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-INCO-DEV-3
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
VILLEURBANNE
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.