Objective The health effects of exposures to fallout from Soviet nuclear weapons testing among the residents living nearby the Semipalatinsk nuclear test site in Kazakhstan are not well investigated. There are reports with contradicting results coming from the studies conducted on two independent cohorts: “historical” and “new”. Both use different control groups and dosimetric methods. The two cohorts have a high probability of including the same individuals. There is a need to investigate possibilities to merge them in order to avoid duplication of efforts and resources for future studies of the health effects in these populations. The main objectives of our feasibility study include:• developing and testing mechanisms for identification of cohort members in the two cohorts;• identification and testing of data linkage mechanisms;• determination of the outcomes that can be studied (cancer and non-cancer diseases);• setting up and testing procedures for follow-up;• identification of case ascertainment mechanisms and sources, depending on the outcome;• characterization and validation of dose assessment methods used in the two cohorts;• investigation of the feasibility to collect data on confounding factors;• assessing the availability of biological samples and their potential use in the future.The project will bring together scientists from Europe, Kazakhstan and Japan with the aim of developing a proposal for a future prospective full scale epidemiological study to address the dose-effect relationship for both cancer and non-cancer effects from low to moderate chronic doses, if the feasibility is demonstrated. To achieve the overall objective it is proposed to set-up a consortium that have considerable experience in epidemiological studies on populations residing around the Semipalatinsk nuclear test site and/or who have been extensively involved in the low dose risk research. The group will include European and international scientists with expertise in epidemiology, dosimetry, radiation biology and clinical medicine. At the end of the project, a detailed report based on the results of the work conducted will be developed, critically reviewed by the External Advisory Board and recommendations for future research needs will be made, if feasible.Other populations exposed to low to moderate dose radiation like in Fukushima or elsewhere can benefit from the outcomes of studying the unique Semipalatinsk cohort and the results will contribute to a better understanding and quantification of radiation risks for low to moderate chronic doses. The proposed project is in line with the Strategic Research Agenda of MELODI. Fields of science medical and health scienceshealth sciencespublic healthepidemiologyengineering and technologyother engineering and technologiesnuclear engineeringmedical and health sciencesclinical medicineoncology Programme(s) FP7-EURATOM-FISSION - EURATOM: Nuclear fission and radiation protection Topic(s) Fission-2012-6.0.1 - Actions supporting programme implementation and other activities Call for proposal FP7-Fission-2012 See other projects for this call Funding Scheme CSA-SA - Support actions Coordinator CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER Address 25 avenue tony garnier 69007 Lyon 7eme France See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Research Organisations Administrative Contact Olaf Kelm (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 306 702,00 Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all DIREKTORATET FOR STRALEVERN OG ATOMSIKKERHET Norway EU contribution € 0,00 Address Grini naeringspark 13 1332 Osteraas See on map Region Norge Oslo og Viken Viken Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Astrid Liland (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window BUNDESAMT FUER STRAHLENSCHUTZ Germany EU contribution € 50 450,00 Address Willy-brandt-strasse 5 38226 Salzgitter See on map Region Niedersachsen Braunschweig Salzgitter, Kreisfreie Stadt Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Susan Fischer Links Contact the organisation Opens in new window Website Opens in new window INSTITUTE OF RADIATION SAFETY AND ECOLOGY OF THE NATIONAL NUCLEAR CENTER OF KAZAKHSTAN Kazakhstan EU contribution € 156 478,00 Address Krasnoarmeyskaya 2 071100 Kurchatov See on map Activity type Research Organisations Administrative Contact Sergey Lukashenko (Mr.) Links Contact the organisation Opens in new window Website Opens in new window SCIENTIFIC RESEARCH INSTITUTE OF RADIATION MEDICINE AND ECOLOGY NIIRME Kazakhstan EU contribution € 39 590,00 Address Gangarina 258 490007 Semipatatinsk See on map Activity type Research Organisations Administrative Contact Talgat Muldagaliev (Dr.) Links Contact the organisation Opens in new window Website Opens in new window NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES Japan EU contribution € 271 780,00 Address 9-1 anagawa 4-chome, inage-ku, chiba-shi 263-8555 Chiba See on map Activity type Research Organisations Administrative Contact Kazuo Sakai (Dr.) Links Contact the organisation Opens in new window Website Opens in new window MEDICAL RADIOLOGICAL RESEARCH CENTRE - RUSSIAN ACADEMY OF MEDICAL SCIENCES Russia EU contribution € 60 000,00 Address Koroleva street 4 249020 Obninsk See on map Activity type Research Organisations Administrative Contact Andrei Kaprin (Prof.) Links Contact the organisation Opens in new window STATE RESEARCH CENTER - BURNASYAN FEDERAL MEDICAL BIOPHYSICAL CENTER OF FEDERAL MEDICAL BIOLOGICAL AGENCY Russia EU contribution € 60 000,00 Address Ul. zhivopisnaya 46 123182 Moscow See on map Activity type Research Organisations Administrative Contact Aleksey Kolpakov Links Contact the organisation Opens in new window Website Opens in new window
