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Content archived on 2024-06-18

Helical Alleno-Acetylenic Oligomers with High Chiroptical Activity

Objective

"The principal goal of this proposed Marie Curie project is to develop a new class of structurally-stable chiral macromolecules—alleno acetylenic oligomers—with an all-carbon backbone and rigid helical secondary structure that will result in high optical activity. We wish to explore and attain a thorough understanding of the factors that allow a significant increase in the optical activity of these materials. This will be achieved by stabilizing their secondary helical structure by the means described below in the proposal, and by forming assemblies of these helices to yield superstructures, in which the optical activity will be increased as a result of cooperative effects. This research project will provide an innovative route for the synthesis of new structurally-stable helical foldamers, where several strategies will be applied: (i) covalent crosslinking using ring closure metathesis (RMC), (ii) non-covalent cross linking using hydrogen and halogen bonding, (iii) coordinative cross linking, (iv) solvophobic interaction – using various solubilizing groups. Considering the high chiral activity reported for the parent oligomer, the structural stabilization of the crosslinked oligomers and the formation of ordered superstructures are expected to result in novel, optically active oligomeric geometries with record-high chiral activities."

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
EU contribution
€ 192 622,20
Address
Raemistrasse 101
8092 Zuerich
Switzerland

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Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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