Objective
The EI-HCV Network will provide an integrated multidisciplinary and multi-sector training in a range of leading skills relevant to antiviral and immunotherapeutic drug development in the post-genomics era.
The researchers will gain world-class expertise in specialist shortage skills including structural biology, functional genomics (genomic analysis, bioinformatics, transcriptomics) and proteomics. They will also obtain training on a range of specialist instruments (e.g. DNA sequencers, confocal microscopes, gene arrays, mass specs, flow cytometers, bioinformatics clusters, synchrotrons, biophysical instruments etc.). This will be facilitated by an individual-focused and needs-driven structured training program encompassing in-house training, formal courses, workshops and major mobility elements such as training placements. Trainees will have the unique opportunity to be involved in a cross-sector project that will develop antivirals and immuno-therapies from the bench to the bedside. Specifically, the Network will identify new therapeutic interventions for the treatment of hepatitis C virus (HCV) infection.
Chronic HCV infection is frequently associated with severe liver disease including liver cancer. Even the latest treatments are ineffective in a significant proportion of infected individuals. Therefore there is a paramount need to identify new therapies. The Network will: Define HCV receptor binding, fusion and entry events; Determine the structure and functional regions of the HCV glycoproteins and receptors; Isolate and characterise neutralizing monoclonal antibodies and sera; Refine in vitro models to measure infectivity and antiviral effects; Use these advances to develop lead antiviral agents and immuno-therapies suitable for clinical trial.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences clinical medicine oncology liver cancer
- medical and health sciences health sciences infectious diseases RNA viruses hepatitis C
- natural sciences physical sciences optics microscopy confocal microscopy
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antivirals
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NOTTINGHAM
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.